150079-72-4Relevant articles and documents
2-bromo-2-nitropropane/zn promoted reductive cyclizations of ortho-carbonyl, imino, or azo substituted nitrobenzenes
Kim, Byeong Hyo,Lee, Yoon Seok,Kwon, Woong,Jin, Youngoo,Tak, Jung Ae,Jun, Young Moo,Baik, Woonphil,Lee, Byung Min
, p. 2581 - 2592 (1998)
Under the mild conditions, reductive cyclizations of 2-nitrobenzaldehydes, 2'-nitroacetophenone, and N-(2-nitrobenzylidene)anilines were accomplished in the presence of 2-bromo-2-nitropropane/Zn in methanolic solution. Under the similar conditions in MeOH/CH2Cl2, o-nitro-substituted phenylazobenzenes have been converted into 2-aryl-2H-benzotriazoles via reductive cyclizations that are widely used as UV absorbers. Synthesis and mechanistic details are discussed.
Electrochemical synthesis of 2,1-benzisoxazoles by controlled potential cathodic electrolysis
Kim, Byeong Hyo,Jim, Young Moo,Choi, Yong Rack,Lee, Doo Byung,Baik, Woonphil
, p. 749 - 754 (1998)
Using a divided cell, reductive cyclization of nitroarene compounds into 2,1-benzisoxazoles in .mild conditions was successfully accomplished by the controlled potential cathodic electrolysis reactions. Optimum reaction potential of each reaction was determined based on cyclic voltametric behavior in methanol solution at Pb or Ft cathode, and Pt anode.
Gold-Catalyzed Intermolecular Formal [4 + 2 + 2]-Cycloaddition of Anthranils with Allenamides
Wang, Cheng,Xu, Guangyang,Shao, Ying,Tang, Shengbiao,Sun, Jiangtao
supporting information, p. 5990 - 5994 (2020/08/12)
The construction of eight-membered rings is a challenging issue due to unfavorable transannular strain and entropic barriers. We report herein a gold-catalyzed formal [4 + 2 + 2] cycloaddition reaction of anthranils with allenamides to deliver oxa-bridged eight-membered heterocycles in accepted yields with unique E/Z configuration. Moreover, the asymmetric [4 + 2 + 2] cycloaddition by using chiral phosphoramidite gold catalyst has also been conducted.
Vasicine from Adhatoda vasica as an organocatalyst for metal-free Henry reaction and reductive heterocyclization of o-nitroacylbenzenes
Sharma, Sushila,Kumar, Manoranjan,Bhatt, Vinod,Nayal, Onkar S.,Thakur, Maheshwar S.,Kumar, Neeraj,Singh, Bikram,Sharma, Upendra
supporting information, p. 5003 - 5008 (2016/10/25)
Vasicine, a quinazoline alkaloid, from the leaves of Adhatoda vasica, has been utilized as an efficient catalyst for metal and base free Henry reaction of various aldehydes with nitro alkanes. The method can be used in the synthesis of various β-nitro alcohols under mild reaction conditions without use of hazardous organic solvents and expensive catalysts. Vasicine is also applied successfully for one pot synthesis of 2,1-benzisoxazoles from o-nitroacylbenzenes in good yields under mild conditions.