150114-85-5

Basic information

• Product Name: N-(tert-butyloxycarbonyl)-L-valyl-L-phenylalanine (methoxyethoxy)ethyl ester
• Synonyms: N-(tert-butyloxycarbonyl)-L-valyl-L-phenylalanine (methoxyethoxy)ethyl ester
• CAS NO: 150114-85-5
• Molecular Weight: 466.575
• Mol File: 150114-85-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(tert-butyloxycarbonyl)-L-valyl-L-phenylalanine (methoxyethoxy)ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-(tert-butyloxycarbonyl)-L-valyl-L-phenylalanine (methoxyethoxy)ethyl ester(150114-85-5)
• EPA Substance Registry System: N-(tert-butyloxycarbonyl)-L-valyl-L-phenylalanine (methoxyethoxy)ethyl ester(150114-85-5)

Safety Data

• Hazardous Substances Data: 150114-85-5(Hazardous Substances Data)

Upstream product

• 13734-41-3 t-Boc-L-valine 
• 111-77-3 2-(2-methoxyethoxy)ethyl alcohol 
• 63-91-2 L-phenylalanine 

Downstream Products

• 156311-02-3 N-(allyloxycarbonyl)-O-(2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-α-D-galactopyranosyl)-L-serilvalylphenylalanine (methoxyethoxy)ethyl ester 
• 197727-46-1 (S)-2-((S)-2-Amino-3-methyl-butyrylamino)-3-phenyl-propionic acid 2-(2-methoxy-ethoxy)-ethyl ester 
• 108334-64-1 N-tert-butyloxycarbonyl-L-valyl-L-phenylalanine 

Relevant articles and documents

Chemoselective removal of protecting groups from O-glycosyl amino acid and peptide (methoxyethoxy)ethyl esters using lipases and papain

The selective C-terminal deprotection of O-glycopeptide (methoxyethoxy)ethyl esters is achieved under mild conditions (pH 6.6, 37°C) by enzymatic hydrolysis using papain or lipase M from Mucor javanicus to give building blocks useful for chain-extending glycopeptide synthesis. On the other hand, the selective removal of acetyl protecting groups from the saccharide portion of glycopeptides is accomplished by alternative enzymatic hydrolysis with lipase WG from wheat germ to furnish model substrates for enzymatic glycosyl transfer reactions in order to extend the carbohydrate side chain of these conjugates.