150125-75-0

Upstream product

• 120390-75-2 (R)-(+)-α-<(tert-butyldimethylsilyl)oxy>-benzeneacetonitrile 
• 150125-74-9 (R)-1-<<(tert-butyldimethylsilyl)oxy>-1-phenylethan-2-yl>-amine 

Downstream Products

• 154049-20-4 bis <(1R)-1-hydroxyphenyl-ethan-2-yl> amine 
• 150125-95-4 (3R,8R,12R,17R)-3,8,12,17-tetraphenyl-1,10-bis(p-tolylsulfonyl)-1,10-diaza-4,7,13,16-tetraoxacyclooctadecane 
• 150125-93-2 (2S,3R,8R,12R,17R,18S)-2,18-diethyl-1-methyl-3,8,12,17-tetraphenyl-10-(p-tolylsulfonyl)-1,10-diaza-4,7,13,16-tetraoxacyclooctadecane 
• 150125-92-1 (2S,3R,8R,12R,17R,18S)-3,8,12,17-tetraphenyl-10-(p-tolylsulfonyl)-1,2,18-trimethyl-1,10-diaza-4,7,13,16-tetraoxacyclooctadecane 
• 150125-91-0 N,N-bis<(R)-1-phenyl-1-<2-ethoxy>ethan-2-yl>-p-toluenesulfonamide 
• 150125-94-3 (3R,17R)-3,17-diphenyl-1,10-bis(p-tolylsulfonyl)-1,10-diaza-4,7,13,16-tetraoxacyclooctadecane 
• 150126-01-5 (2S,3R,8R,12R,17R,18S)-2,18-diethyl-1-methyl-3,8,12,17-tetraphenyl-1,10-diaza-4,7,13,16-tetraoxacyclooctadecane 
• 150126-00-4 (2S,3R,8R,12R,17R,18S)-3,8,12,17-tetraphenyl-1,2,18-trimethyl-1,10-diaza-4,7,13,16-tetraoxacyclooctadecane 
• 150125-99-8 (3R,8R,12R,17R)-3,8,12,17-tetraphenyl-1,10-diaza-4,7,13,16-tetraoxacyclooctadecane 
• 150125-90-9 N,N-bis<(R)-1-(2-hydroxyethoxy)-1-phenylethan-2-yl>-p-toluenesulfonamide 
• 150125-96-5 (3R,17R)-3,17-diphenyl-1,10-diaza-4,7,13,16-tetraoxacyclooctadecane 
• 150125-89-6 N,N-bis<(R)-1-hydroxy-1-phenylethan-2-yl>-p-toluenesulfonamide 
• 150125-87-4 N,N-bis<(R)-1-<(tert-butyldimethylsilyl)oxy>-1-phenylethan-2-yl>-p-toluenesulfonamide 

Relevant academic research and scientific papers

Synthesis of Chiral Diaza-18-crown-6 Derivatives from Optically Active Diethanolamines

Homotopic 1,10-diaza-18-crown-6 derivatives with two, four, and six chiral centers have been prepared in optically active form from diethanolamines via a cyclization reaction with tosylates 39 and 48.The requisite optically active diethanolamines were prepared from chiral cyanohydrins and chiral ethanolamines by a one-pot Grignard-transimination-reduction or a one-pot reduction-transimination-reduction procedure.Yields were strongly affected by the size of the substituents α to the nitrogen atom.The stereoselectivity of the diethanolamine synthesis was found to depend on the configuration of the ethanolamine used.