15017-45-5

Upstream product

• 2927-34-6 3,4-difluorotoluene 
• 85118-01-0 alpha-bromo-3,4-difluorotoluene 
• 1068-90-2 2-acetylaminomalonic acid diethyl ester 

Downstream Products

• 198474-90-7 (S)-2-((tert-butoxycarbonyl)amino)-3-(3,4-difluorophenyl)propanoic acid 
• 266360-51-4 2-acetylamino-3-(3,4-difluoro-phenyl)-propionic acid 
• 266360-57-0 N-Acetyl-3,4-difluoro-D-phenylalanine 
• 249648-08-6 3,4-difluoro-D-phenylalanine 
• 31105-90-5 (L)-2-amino-3-(3,4-difluorophenyl)propanoic acid 
• 32133-36-1 2-amino-3-(3,4-difluorophenyl)propanoic acid 

Relevant academic research and scientific papers

Piperazine derivatives

This invention relates to piperazine derivatives of the formula: wherein each symbol is as defined in the description, and its pharmaceutically acceptable salt, to processes for preparation thereof, to pharmaceutical composition comprising the same, and to a use of the same for treating or preventing Tachykinin-mediated diseases in human being or animals.

Synthesis of a complete set of L-difluorophenylalanines, L-(F2)Phe, as molecular explorers for the CH/π interaction between peptide ligand and receptor

A complete set of difluorophenylalanines in the L-configuration [L- (F2)Phe] (namely, L-(2,3-F2)Phe, L-(2,4-F2)Phe, L-(2,5-F2)Phe, L-(2,6- F2)Phe, L-(3,4-F2)Phe, L-(3,5-F2)Phe) w