15018-52-7

Basic information

• Product Name: 5-benzyl-1,3-dimethylpyrimidine-2,4,6(1H,3H,5H)-trione
• Synonyms: 2,4,6(1H,3H,5H)-pyrimidinetrione, 1,3-dimethyl-5-(phenylmethyl)-; 5-Benzyl-1,3-dimethylpyrimidine-2,4,6(1H,3H,5H)-trione
• CAS NO: 15018-52-7
• Molecular Formula: C₁₃H₁₄N₂O₃
• Molecular Weight: 246.2619
• Mol File: 15018-52-7.mol
• Article Data: 19

Chemical Properties

• Boiling Point: 360°C at 760 mmHg
• Flash Point: 154.4°C
• Density: 1.254g/cm³
• Vapor Pressure: 2.29E-05mmHg at 25°C
• Refractive Index: 1.571
• CAS DataBase Reference: 5-benzyl-1,3-dimethylpyrimidine-2,4,6(1H,3H,5H)-trione(CAS DataBase Reference)
• NIST Chemistry Reference: 5-benzyl-1,3-dimethylpyrimidine-2,4,6(1H,3H,5H)-trione(15018-52-7)
• EPA Substance Registry System: 5-benzyl-1,3-dimethylpyrimidine-2,4,6(1H,3H,5H)-trione(15018-52-7)

Safety Data

• Hazardous Substances Data: 15018-52-7(Hazardous Substances Data)

Upstream product

• 769-42-6 1,3-dimethylbarbituric acid 
• 100-44-7 benzyl chloride 
• 100-52-7 benzaldehyde 
• 54459-73-3 5-benzylidene-1,3-dimethyl-pyrimidine-2,4,6-trione 
• 58378-09-9 1,3,1',3'-tetramethylhydurilic acid 
• 21544-73-0 5,5-dichloro-1,3-dimethyl-2,4,6(1H,3H,5H)-pyrimidinetrione 
• 100-51-6 benzyl alcohol 
• 620-40-6 tribenzylamine 
• 103-83-3 N,N'-dimethylbenzylamine 
• 77-78-1 dimethyl sulfate 
• 137-07-5 2-amino-benzenethiol 
• 95-54-5 1,2-diamino-benzene 
• 613-31-0 9,10-dihydroanthracene 

Downstream Products

• 13154-57-9 2,6-di-tert-butyl-4-(tert-butylperoxy)-4-methylcyclohexa-2,5-dien-1-one 
• 54459-73-3 5-benzylidene-1,3-dimethyl-pyrimidine-2,4,6-trione 
• 1167472-68-5 5-benzyl-6-methoxy-1,3-dimethyl-1H-pyrimidine-2,4-dione 
• 1195989-30-0 5-benzyl-1,3-dimethyl-5-(3-methyl-but-2-enyl)-pyrimidine-2,4,6-trione 
• 39260-04-3 1,3-dimethylpyrimido<4,5-b>quinoline-2,4(1H,3H)-dione 

Relevant articles and documents

Sequential one-pot bimetallic Ir(III)/Pd(0) catalysed mono-/bis-alkylation and spirocyclisation processes of 1,3-dimethylbarbituric acid and allenes

Microwave assisted indirect functionalization of alcohols with 1,3-dimethylbarbituric acid followed by spirocyclisation employing a sequential one-pot Ir(iii)/Pd(0) catalysed process, involving the formation of three new C-C bonds, one spirocyclic ring and one di- or tri-substituted exocyclic alkene, is described. The Royal Society of Chemistry.

PHOTOLABILE BARBITURATE COMPOUNDS

The present disclosure provides a redox initiator system for initiating polymerization comprising an oxidizing agent, a photolabile reducing agent derived from a barbiturate, and a transition metal complex that participates in a redox cycle. On exposure to actinic radiation, such as UV, the photolabile compound photolyzes, releasing the reducing agent and initiating the redox-initiated polymerization.

Method for greenly synthesizing 5-hydroxy-5-alkyl disubstituted barbituric acid derivative by amine catalysis of air oxidation

The invention relates to the field of oxidative synthesis, and in particular, relates to a 5-hydroxy-5-alkyl disubstituted barbituric acid derivative greenly synthesized by amine catalysis of air oxidation and a method thereof. The amine-catalyzed oxidation reaction of a 5-substituted 1,3-dimethylbarbituric acid derivative is studied; reaction catalysts and solvents are screened, hydroxylation ofalpha-C-H of 5-aryl or benzyl substituted barbituric acid compounds is found out to be realized through catalytic reaction under different conditions. The method has the following characteristics: (1)air is used as the source of hydroxyl functional groups, so the requirements of green development are met; (2) easily available and cheap alkali R3N rather than expensive metal catalysts is used; and(3) stoichiometric harmful phosphine compounds are prevented from being used as additives and reductants.