150267-59-7Relevant academic research and scientific papers
Synthetic studies on diterpenoid quinones with interleukin-1 inhibitory activity. Total synthesis of (±)- and (+)-triptoquinone A
Shishido,Goto,Miyoshi,Takaishi,Shibuya
, p. 406 - 414 (2007/10/02)
An efficient first total synthesis of (±)- and (+)-triptoquinone A (1), a novel diterpenoid quinone with significant inhibitory activity against interleukin-1 releases, has been completed. Birch reduction of tricyclic enone (±)-7, prepared from known 6-me
Diastereoselective Total Syntheses of (+/-)-Triptoquinone B and C
Shishido, Kozo,Goto, Kiyoto,Tsuda, Asae,Takaishi, Yoshihisa,Shibuya, Masayuki
, p. 793 - 794 (2007/10/02)
The first and efficient total syntheses of (+/-)-triptoquinone B 1 and C 2 have been achieved from the allyl ether 3; the key steps are the construction of the four contiguous stereogenic centers present in 2 by the Mn(III) mediated oxidative free radical cyclisation followed by metal hydride reduction.
