1503-03-3

Basic information

• Product Name: METHYL 3-AMINO-5-HYDROXYPYRAZINE-2-CARBOXYLATE
• Synonyms: METHYL 3-AMINO-5-HYDROXYPYRAZINE-2-CARBOXYLATE;3-AMino-5-oxo-4,5-dihydro-pyrazine-2-carboxylic acid Methyl ester
• CAS NO: 1503-03-3
• Molecular Formula: C6H7N3O3
• Molecular Weight: 169.14
• Mol File: 1503-03-3.mol
• Article Data: 2

Chemical Properties

• Melting Point: 220-260 °C (decomp)
• Appearance: /
• Density: 1.58±0.1 g/cm3(Predicted)
• PKA: 9.54±0.60(Predicted)
• CAS DataBase Reference: METHYL 3-AMINO-5-HYDROXYPYRAZINE-2-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 3-AMINO-5-HYDROXYPYRAZINE-2-CARBOXYLATE(1503-03-3)
• EPA Substance Registry System: METHYL 3-AMINO-5-HYDROXYPYRAZINE-2-CARBOXYLATE(1503-03-3)

Safety Data

• Hazardous Substances Data: 1503-03-3(Hazardous Substances Data)

Upstream product

• 16298-03-6 Methyl 3-amino-2-pyrazinecarboxylate 

Downstream Products

• 28643-16-5 3-amino-5-chloro-pyrazine-2-carboxylic acid methyl ester 

Relevant articles and documents

2 -AMINO-4 - (PYRIDIN- 2 -YL) - 5, 6 -DIHYDRO-4H- 1, 3 -OXAZINE DERIVATIVES AND THEIR USE AS BACE-1 AND/OR BACE - 2 INHIBITORS

The invention relates to novel oxazine derivatives of formula (I), and pharmaceutically acceptable salts thereof, in which all of the variables are as defined in the specification, pharmaceutical compositions thereof, combinations thereof, and their use as medicaments, particularly for the treatment of Alzheimer's Disease or diabetes via inhibition of BACE-1 or BACE-2.