15031-42-2

Basic information

• Product Name: 1,4-Dimethyl-1,2-dihydropyridine-2-one
• Synonyms: 1,4-Dimethyl-1,2-dihydropyridine-2-one;1,4-Dimethyl-2(1H)-pyridone
• CAS NO: 15031-42-2
• Molecular Formula: C₇H₉NO
• Molecular Weight: 123.15
• Mol File: 15031-42-2.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 261.6°C at 760 mmHg
• Flash Point: 121.7°C
• Appearance: /
• Density: 1.038g/cm³
• Vapor Pressure: 0.0114mmHg at 25°C
• Refractive Index: 1.508
• CAS DataBase Reference: 1,4-Dimethyl-1,2-dihydropyridine-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-Dimethyl-1,2-dihydropyridine-2-one(15031-42-2)
• EPA Substance Registry System: 1,4-Dimethyl-1,2-dihydropyridine-2-one(15031-42-2)

Safety Data

• Hazardous Substances Data: 15031-42-2(Hazardous Substances Data)

Usage

General Description

1,4-Dimethyl-1,2-dihydropyridine-2-one is a chemical compound with the molecular formula C7H9NO. It is a derivative of dihydropyridine and belongs to the class of organic compounds known as 1,4-dihydropyridines. 1,4-Dimethyl-1,2-dihydropyridine-2-one is commonly used in the synthesis of various pharmaceutical drugs, especially calcium channel blockers, which are used to treat high blood pressure and angina. Additionally, it exhibits antioxidant properties, making it potentially useful in the development of anti-aging and skincare products. 1,4-Dimethyl-1,2-dihydropyridine-2-one is a versatile compound with various potential applications in pharmaceutical and cosmetic industries.

InChI:InChI=1/C7H9NO/c1-6-3-4-8(2)7(9)5-6/h3-5H,1-2H3

Upstream product

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Downstream Products

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• 121471-25-8 [(4R,5R)-5-(Hydroxy-diphenyl-methyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-diphenyl-methanol; compound with 1,4-dimethyl-1H-pyridin-2-one 
• 100465-37-0 2,5-Dimethyl-2-aza-bicyclo[2.2.0]hex-5-en-3-one 
• 110901-43-4 (1R,2R,5S,6S)-3,7,9,11-Tetramethyl-3,7-diaza-tricyclo[4.2.2.2^2,5]dodeca-9,11-diene-4,8-dione 
• 1393102-76-5 6-[2-(cyclohex-3-en-1-yl)ethyl]-1,4-dimethyl-pyridin-2(1H)-one 
• 1393102-80-1 6-cyclohexyl-1,4-dimethylpyridin-2(1H)-one 

Relevant articles and documents

Kinetics of solid state photodimerization of 1,4-dimethyl-2-pyridinone in its molecular compound

The [4 + 4] photodimerization of 1,4-dimethyl-2-pyridinone (A) in its molecular compound with 1,1,6,6-tetraphenyl-2,4-hexadiyne-1,6-diol (I) was investigated by irradiation of a single crystal of the compound. The conversion to the product in a single-cry

Thermal Behavior Analysis of Two Synthesized Flavor Precursors of N-alkylpyrrole Derivatives

To expand the library of pyrrole-containing flavor precursors, two new flavor precursors—methyl N-benzyl-2-methyl-5-formylpyrrole-3-carboxylate (NBMF) and methyl N-butyl-2-methyl-5-formylpyrrole-3-carboxylate (NUMF)—were synthesized by cyclization, oxidation, and alkylation reactions. Thermogravimetry (TG), differential scanning calorimeter, and pyrolysis–gas chromatography/mass spectrometry were utilized to analyze the thermal degradation behavior and thermal degradation products of NBMF and NUMF. The TG-DTG curve indicated that the maximum mass loss rates of NBMF and NUMF appear at 310 and 268°C, respectively. The largest peaks of NBMF and NUMF showed by the differential scanning calorimeter curve were 315 and 274°C, respectively. Pyrolysis–gas chromatography/mass spectrometry detected small molecule fragrance compounds appeared during thermal degradation, such as 2-methylpyrrole, 1-methylpyrrole-2-carboxylic acid methyl ester, limonene, and methyl formate. Finally, the thermal degradation mechanism of NBMF and NUMF was discussed, which provided a theoretical basis for their application in tobacco flavoring additives.

Asymmetric Homogeneous Hydrogenation of 2-Pyridones

An asymmetric homogeneous hydrogenation of 2(1H)-pyridones has been developed, using a ruthenium complex bearing two chiral N-heterocyclic carbene (NHC) ligands. To the best of our knowledge, the presented reaction is the first example of a homogeneous asymmetric conversion of 2-pyridones into the corresponding enantioenriched 2-piperidones.