150322-60-4

Upstream product

• 1400867-30-2 2-(2-fluorophenyl)-2-(2-methoxy-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetonitrile 
• 23719-80-4 cyclopropylmagnesium bromide 
• 28783-41-7 6,7-dihydro-4H-thieno[3,2-c]pyridine hydrochloride 
• 55142-78-4 5-benzyl-4,5,6,7-tetrahydro-thieno[3,2-c]-pyridine 
• 1056464-85-7 2-bromo-5-benzyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridine 
• 1056464-86-8 2-methoxy-5-benzyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridine 
• 1056549-88-2 2-methoxy-4,5,6,7-tetrahydrothieno[3,2-c]pyridine 
• 446-48-0 o-fluorobenzyl bromide 
• 326-62-5 2-fluorophenyl acetonitrile 
• 1232674-98-4 2-bromo-2-(2-fluorophenyl)acetonitrile 
• 4333-56-6 cyclopropyl bromide 

Downstream Products

• 1400867-31-3 C₁₈H₁₈FNO₂S 

Relevant academic research and scientific papers

Method for preparing Prasugrel intermediate

The invention belongs to the technical field of pharmaceutical synthesis and particularly relates to a method for preparing a Prasugrel intermediate. The method is characterized by subjecting a compound (I) shown in the description to a reaction with a Gr

Efficient synthesis of prasugrel, a novel P2Y12 receptor inhibitor

An efficient synthesis of prasugrel, a novel P2Y12 receptor inhibitor, is described. The cyclopropyl-phenylethanone intermediate was prepared by cyanide substitution, bromination, N-substitution, and the Grignard reaction. After acid hydrolyzation of the methyl ether and subsequent acetylation, the title product was obtained with a total yield of 21% after 10 linear steps from simple and commercially available raw materials.