150323-09-4

Upstream product

• 4143-61-7 diethyl diazodicarboxylate 
• 143978-73-8 1-tert-butoxycarbonyl-4(R)-hydroxy-L-proline tert-butylamide 
• 108-95-2 phenol 

Downstream Products

• 1237938-21-4 N-t-butyl-4(S)-phenoxy-L-prolineamide trifluoroacetic acid salt 

Relevant academic research and scientific papers

HIV protease inhibitors useful for the treatment of AIDS

Compounds of formula STR1 where R1 and R2 are independently hydrogen or optionally-substituted C1-4 alkyl or aryl, or R1 and R2 are joined together to form a monocyclic or bicyclic ring system, are HIV protease inhibitors. These compounds are useful in the treatment of infection by HIV and in the treatment of AIDS, either as compounds, pharmaceutically acceptable salts, pharmaceutical composition ingredients, whether or not in combination with other antivirals, immunomodulators, antibiotics or vaccines. Methods of treating AIDS and methods of treating infection by HIV are also described.