150370-50-6

Basic information

• Product Name: 1-amino-2,3,4,6-tetra-O-benzyl-1-deoxy-β-D-mannopyranose
• Synonyms: 1-amino-2,3,4,6-tetra-O-benzyl-1-deoxy-β-D-mannopyranose
• CAS NO: 150370-50-6
• Molecular Weight: 539.671
• Mol File: 150370-50-6.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: 1-amino-2,3,4,6-tetra-O-benzyl-1-deoxy-β-D-mannopyranose(CAS DataBase Reference)
• NIST Chemistry Reference: 1-amino-2,3,4,6-tetra-O-benzyl-1-deoxy-β-D-mannopyranose(150370-50-6)
• EPA Substance Registry System: 1-amino-2,3,4,6-tetra-O-benzyl-1-deoxy-β-D-mannopyranose(150370-50-6)

Safety Data

• Hazardous Substances Data: 150370-50-6(Hazardous Substances Data)

Usage

Molecular structure

A complex chemical compound with a mannose sugar backbone, benzyl groups, and an amino group.

Common use

Organic chemistry research, specifically in the synthesis of carbohydrates and glycoconjugates.

Benzyl groups

Provide protection for the hydroxyl groups on the mannose sugar, allowing for selective reactions to occur at specific sites on the molecule.

Amino group

Adds versatility to the compound, enabling it to participate in various chemical reactions and potentially serve as a building block for more complex molecules.

Role

Plays a crucial role in the development and study of carbohydrate-based compounds and their applications in various fields.

Upstream product

• 38768-81-9 2,3,4,6-Tetra-O-benzyl-α-D-glucose 
• 139189-57-4 2,3,4,6-tetra-O-benzyl-D-glucononitrile 
• 99701-64-1 N-((2S,3R,4S,5R,6R)-3,4,5-tris(benzyloxy)-6-((benzyloxy)-methyl)-tetrahydro-2H-pyran-2-yl)-2,2,2-trichloroacetamide 
• 213202-73-4 2,3,4,6-tetra-O-benzyl-1-O-methanesulfonyl-D-glucopyranoside 
• 4291-69-4 2,3,4,6-Tetra-O-benzyl-D-glucopyranose 
• 4196-35-4 2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl bromide 
• 20379-61-7 2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl azide 
• 13992-25-1 1-azido-1-deoxy-β-D-glucopyranoside tetraacetate 
• 572-09-8 2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl bromide 
• 4451-36-9 2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl chloride 
• 20379-59-3 D-glucopyranosyl azide 
• 566200-25-7 ((2R,3R,4S,5R,6R)-3,4,5-Tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl)-carbamic acid allyl ester 
• 604-69-3 β-D-glucose pentaacetate 
• 155167-02-5 2,3,4,6-tetra-O-benzyl-D-mannononitrile 

Downstream Products

• 222296-27-7 6-(2,3,4,6-tetra-O-benzyl-β-D-mannopyranosylamino)-9-(2-(trimethylsilyl)-ethoxymethyl)-purine 
• 1607430-75-0 ethyl (S)-3-(1,3-diisopropylureido)-4-oxo-4-[(2R,3R,4S,5R,6R)-3,4,5-tris(benzyloxy)-6-(benzyloxymethyl)tetrahydro-2H-pyran-2-ylamino]butanoate 
• 1607430-53-4 ethyl (R)-3-(1,3-diisopropylureido)-4-oxo-4-[(2R,3R,4S,5R,6R)-3,4,5-tris(benzyloxy)-6-(benzyloxymethyl)tetrahydro-2H-pyran-2-ylamino]butanoate 
• 1453084-77-9 C₄₀H₄₀BrNO₅ 
• 253425-83-1 (2R,3R,4S,5R,6R)-3,4,5-tris(benzyloxy)-6-((benzyloxy)methyl)-N-(4-methoxyphenyl)tetrahydro-2H-pyran-2-amine 
• 1314650-84-4 C₄₇H₅₉N₃O₁₀ 
• 1314650-83-3 C₄₈H₅₃N₃O₁₀ 
• 1314650-81-1 C₄₁H₄₆N₂O₈ 

Relevant articles and documents

Anti-tick-borne encephalitis virus activity of novel uridine glycoconjugates containing amide or/and 1,2,3-triazole moiety in the linker structure

Tick-borne encephalitis virus (TBEV) transmitted by ticks is a pathogen of great medical importance. As still no effective antiviral treatment is available, in the present study, a series of uridine glycoconjugates containing amide or/and 1,2,3-triazole moiety in the linker structure was synthesized and evaluated for the antiviral activity against two strains of TBEV: a highly virulent Hypr strain and less virulent Neudoerfl strain, using standardized previously in vitro assays. Our data have shown that four compounds from the series (18–21) possess strong activity against both TBEV strains. The half maximal inhibitory concentration (IC50) values of compounds 18–21 were between 15.1 and 3.7 μM depending on the virus strain, which along with low cytotoxicity resulted in high values of the selectivity index (SI). The obtained results suggest that these compounds may be promising candidates for further development of new therapies against flaviviruses.

Acid-catalysed rearrangement of glycosyl trichloroacetimidates: a novel route to glycosylamines

A novel route to glycosylamines has been developed. Treatment of glycosyl trichloroacetimidates with TMSOTf under glycosylation conditions, but in the absence of an acceptor, resulted in complete rearrangement of the trichloroacetimidates into the corresp

A new method for the stereoselective synthesis of α- and β-glycosylamines using the Burgess reagent

Although glycosylamines constitute an important group of carbohydrates from the standpoint of biology and medicine, methods for their synthesis typically lack substrate generality and/or result in variable stereoselectivity, especially in complex contexts