150438-01-0Relevant articles and documents
Nonpeptide angiotensin II receptor antagonists. 2. Design, synthesis, and structure-activity relationships of 2-alkyl-4-(1H-pyrrol-1-yl)-1H-imidazole derivatives: Profile of 2-propyl-1-[[2'-(tetrazol-5-yl)-[1,1'-biphenyl]-4- yl]-methyl]-4-[2-(trifluoroace
Sircar,Hodges,Quin III,Bunker,Winters,Edmunds,Kostlan,Connolly,Kesten,Hamby,Topliss,Keiser,Panek
, p. 2253 - 2265 (2007/10/02)
A novel series of nonpeptide angiotensin II (AII) receptor antagonists containing a 1H-pyrrol-1-yl moiety at the 4-position of the imidazole have been developed. The pyrrole group occupies the same lipophilic pocket at the receptor as the chloro group in