150447-48-6Relevant academic research and scientific papers
New approach to 4-phenyl-β-aminotetralin from 4-(3-halophenyl)tetralen-2-ol phenylacetate
Vincek, Adam S.,Booth, Raymond G.
supporting information; experimental part, p. 5107 - 5109 (2009/12/01)
Mixed trifluoroacetyl phenylacetyl anhydride and 3-halostyrenes (fluoro, chloro, and bromo) or vinylcycloalkanes (cyclohexyl and cyclooctyl), undergo cascade Friedel-Crafts cycli-acylalkylation, enolization, and O-acylation to give 4-substituted tetralen-
THERAPEUTIC COMPOUNDS
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Page/Page column 54, (2009/01/23)
The invention relates to protein binding interacting/binding compounds and methods of identifying and using them. The invention further relates to pharmaceutical compositions and methods for treating 5-HT2C disorders, including diseases and disorders medi
Synthesis and Pharmacological Evaluation of 1-Phenyl-3-amino-1,2,3,4-tetrahydronaphthalenes as Ligands for a Novel Receptor with ?-like Neuromodulatory Activity
Wyrick, Steven D.,Booth, Raymond G.,Myers, Andrew M.,Owens, Constance E.,Kula, Nora S.,et al.
, p. 2542 - 2551 (2007/10/02)
Certain novel 1-phenyl-3-amino-1,2,3,4-tetrahydronaphthalenes (1-phenyl-3-aminotetralins, PATs) produced stimulation (ca. 30percent above basal levels) of tyrosine hydroxylase (TH) activity at 0.1 μM concentrations in rodent brain tissue. This effect on T
