150495-37-7

Upstream product

• 157589-11-2 1-(4-Chloro-phenyl)-2-[4-(4-chloro-phenyl)-3,6-dihydro-2H-pyridin-1-yl]-ethanone 
• 536-38-9 4-chlorobenzoylmethyl bromide 
• 51304-61-1 4-(4-chlorophenyl)-1,2,3,6-tetrahydropyridine hydrochloride 

Relevant academic research and scientific papers

Benzyl cation initiated intramolecular cyclizations. Synthesis of 1-azabicyclo[3.2.1]octene derivatives

Benzyl cation inititiated intramolecular cyclization reactions with conjugated C-C double bonds were performed providing rac. endo-exo isomers of 1-azabicyclo[3.2.1]octenes (2 and 3). Formation of the endo isomer 2 is favoured. Compounds 2 possess dopamine uptake inhibitory effect with an additional selective MAO-B enzyme inhibitory potential. The remarkable in vitro effects do not correspond to in vivo antidepressant activity. Johann Ambrosius Barth 1998.

N-hydroxyalkyl-substituted 1,2,3,6-tetrahydro-pyridine and piperidine derivatives

The invention relates to novel N-hydroxy-substituted 1,2,3,6-tetrahydropyridine and piperidine derivatives of the formula STR1 wherein A, B, D, E, G, I and R are as defined in the specification, m is 0, 1 or 2, with the proviso that: m is 0 or 2, or both