150512-87-1

Upstream product

• 117330-40-2 dimethyl 6,6'-dimethyl-2,2'-bipyridine-4,4'-dicarboxylate 
• 345604-52-6 6,6'-dimethyl-4,4'-dicarbomethoxy-2,2'-bipyridine mono-N-oxide 

Downstream Products

• 1399358-70-3 C₂₂H₁₈N₂O₇ 
• 1399358-66-7 dimethyl 6-{[4-(2-methoxy-2-oxoethyl)phenoxy]methyl}-6'-methyl-2,2'-bipyridine-4,4'-dicarboxylate 

Relevant academic research and scientific papers

A water-soluble calix[4]arene-based podand incorporating 4,4′-dicarboxy-2,2′-bipyridine chelating units - Synthesis and complexation properties towards copper ions

A water-soluble calix[4]arene-based podand has been prepared by incorporation, at the lower rim, of two 4,4′-dicarboxy-2,2′- bipyridine units in opposite positions. The association between its coordination and hydrophilic properties were beneficial to the complexation and solubilization of copper(i) in water, even in the presence of bovine serum albumin. The ligand and its corresponding CuI complex have been fully characterized, but attempts to crystallize them have been unsuccessful so far. For this reason, the dinuclear ZnCl2 complex of the organic solvent soluble tetraester intermediate has been crystallized, and subjected to X-ray diffraction analysis, confirming the expected podand-like structure of the ligand. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004.

A new water-soluble ligand based on a calix[4]arene substituted by 2,2′-bipyridine chelating units

A new water-soluble calix[4]arene-based podand was prepared by tethering two 4,4′-dicarboxy-2,2′-bipyridine units on distal phenol rings.

Rare earth macrocyclic complexes and use thereof for reduction of disturbances in an assay using fluorescence

The invention relates to macrocyclic rare earth complexes which consist of at least one rare earth salt complexed by a macrocyclic compound of formula (I): STR1 in which: the bivalent radicals A, B, C and D, which are identical or different, are hydrocarbon chains optionally containing one or more heteroatoms, at least one of said radicals containing at least one molecular unit or essentially consisting of a molecular unit possessing a triplet energy greater than the energy of the emission level of the complexed rare earth ion, at least one of said radicals consisting of a substituted or unsubstituted nitrogen-containing heterocyclic system in which at least one of the nitrogen atoms carries an oxy group, and it being possible for one of the radicals C or D not to exist; and X1 and X2, which are identical or different, are hydrogen or a hydrocarbon chain (CH2)n optionally interrupted by 1 or more heteroatoms, n being an integer from 1 to 10, with the proviso that if the radicals A and/or B are a nitrogen-containing heterocyclic system in which at least one of the nitrogen atoms carries an oxy group, the radicals C and/or D are selected from biquinolines, biisoquinolines, bipyridines, terpyridines, coumarins, bipyrazines, bipyrimidines and pyridines, and to their use for reducing the perturbations in a fluorescent assay.