150536-43-9Relevant academic research and scientific papers
Synthesis of 1,3-benzothiazines by intramolecular dehydrogenative C–S cross-coupling in a flow electrolysis cell
Huang, Chong,Xu, Hai-Chao
, p. 1501 - 1503 (2019)
Dehydrogenative cyclization of thioamides is an attractive approach for the synthesis of S-heterocycles. Reported herein is an electrochemical dehydrogenative cyclization reaction of N-benzyl thioamides in a flow electrolysis cell. The continuous-flow electrosynthesis has addressed the limitations associated with previously reported methods for the cyclization of alkylthioamides and provide a transition metal- and oxidizing reagent-free access to various functionalized 1,3-benzothiazines in good yields.
Ring-Closure Reaction of N-Arylthiomethylaroylamides to 1,3-Benzothiazines
Szabo, Janos,Bani-Akoto, Ernest,Dombi, Gyoergy,Guenther, Gabor,Bernath, Gabor,Fodor, Lajos
, p. 1321 - 1324 (2007/10/02)
N-Arylthiomethylaroylamides substituted with an electron-donating group in the meta position undergo two-directional cyclization in the presence of phosphorus oxychloride to give both positional isomers of the 4H-1,3-benzothiazine derivative.The structure
