150536-48-4Relevant academic research and scientific papers
Nickel-Catalyzed Selective Decarbonylation of α-Amino Acid Thioester: Aminomethylation of Mercaptans
Zhou, Jing-Ya,Tian, Rui,Zhu, Yong-Ming
, p. 12148 - 12157 (2021/09/07)
The nickel-catalyzed aminomethylation of mercaptans has been disclosed that offers efficient and expedient access to synthesize α-aminosulfides. The intramolecular fragment coupling shows excellent chemoselectivity. This transformation shows good functional-group compatibility, tolerates a wide range of electron-withdrawing, electron-neutral, and electron-donating substituents in this process, and can serve as a powerful synthetic tool for the synthesis of α-aminosulfides at a gram scale. Thus, the newly developed methodology enables a facile route for C-S bond formation in a straightforward fashion.
Synthesis and structural characterisation of 927 4H-1,3-benzothiazine derivatives
Fodor, Lajos,Bernath, Gabor,Sinkkonen, Jari,Pihlaja, Kalevi
, p. 927 - 931 (2007/10/03)
The ring-closure reactions of N-arylthiomethylaroylamide derivatives (1a-g) in the presence of phosphorus oxychloride gave 2-aryl-4H-1,3-benzo-thiazines (2a-g). 2-(3-Chlorophenyl)-6-methyl-4H-1,3-benzothiazine (2b) was reduced with Zn to obtain the corres
Ring-Closure Reaction of N-Arylthiomethylaroylamides to 1,3-Benzothiazines
Szabo, Janos,Bani-Akoto, Ernest,Dombi, Gyoergy,Guenther, Gabor,Bernath, Gabor,Fodor, Lajos
, p. 1321 - 1324 (2007/10/02)
N-Arylthiomethylaroylamides substituted with an electron-donating group in the meta position undergo two-directional cyclization in the presence of phosphorus oxychloride to give both positional isomers of the 4H-1,3-benzothiazine derivative.The structure
