150536-48-4

Basic information

• Product Name: N-(4-methylphenylthiomethyl)-4-chlorobenzamide
• Synonyms: N-(4-methylphenylthiomethyl)-4-chlorobenzamide
• CAS NO: 150536-48-4
• Molecular Weight: 291.801
• Mol File: 150536-48-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-(4-methylphenylthiomethyl)-4-chlorobenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-methylphenylthiomethyl)-4-chlorobenzamide(150536-48-4)
• EPA Substance Registry System: N-(4-methylphenylthiomethyl)-4-chlorobenzamide(150536-48-4)

Safety Data

• Hazardous Substances Data: 150536-48-4(Hazardous Substances Data)

Upstream product

• 13855-74-8 4-chloro-N-(hydroxymethyl)benzamide 
• 106-45-6 para-thiocresol 

Downstream Products

• 150536-47-3 2-(4-chlorophenyl)-6-methyl-4H-1,3-benzothiazine 

Relevant articles and documents

Nickel-Catalyzed Selective Decarbonylation of α-Amino Acid Thioester: Aminomethylation of Mercaptans

The nickel-catalyzed aminomethylation of mercaptans has been disclosed that offers efficient and expedient access to synthesize α-aminosulfides. The intramolecular fragment coupling shows excellent chemoselectivity. This transformation shows good functional-group compatibility, tolerates a wide range of electron-withdrawing, electron-neutral, and electron-donating substituents in this process, and can serve as a powerful synthetic tool for the synthesis of α-aminosulfides at a gram scale. Thus, the newly developed methodology enables a facile route for C-S bond formation in a straightforward fashion.

Ring-Closure Reaction of N-Arylthiomethylaroylamides to 1,3-Benzothiazines

N-Arylthiomethylaroylamides substituted with an electron-donating group in the meta position undergo two-directional cyclization in the presence of phosphorus oxychloride to give both positional isomers of the 4H-1,3-benzothiazine derivative.The structure