150544-80-2

Upstream product

• 99124-56-8 3-(1-naphthalenyl)propionyl chloride 
• 90719-32-7 (S)-4-Benzyl-2-oxazolidinone 
• 119377-27-4 (4S)-3-<3-(1-naphthyl)propionyl>-4-benzyloxazolidin-2-one 
• 5437-45-6 Benzyl bromoacetate 

Downstream Products

• 150544-81-3 (4S)-4-benzyl-3-<(2R)-3-carboxy-2-<(1-naphthyl)methyl>propionyl>oxazolidin-2-one 
• 150544-82-4 (4S)-4-benzyl-3-<(2R)-3-<1-<4-<(tert-butyloxycarbonyl)amino>piperidinyl>>carbonyl>-2-<(1-naphthyl)methyl>oxazolidin-2-one 
• 135650-90-7 [1-((R)-3-{(S)-1-((1S,2R,3S)-1-Cyclohexylmethyl-2,3-dihydroxy-5-pyridin-2-yl-pentylcarbamoyl)-2-[1-(2,4-dinitro-phenyl)-1H-imidazol-4-yl]-ethylcarbamoyl}-4-naphthalen-1-yl-butyryl)-piperidin-4-yl]-carbamic acid tert-butyl ester 

Relevant academic research and scientific papers

Renin inhibitors containing a pyridyl amino diol derived C-terminus

Based on the concept of transition-state analogs, a series of nonpeptide renin inhibitors with the new (2S,3R,4S)-2-amino-1-cyclohexyl-3,4-dihydroxy- 6-(2-pyridyl)hexane moiety at the C-terminal functionality were synthesized and evaluated for inhibition