150555-91-2Relevant academic research and scientific papers
A method and intermediates for the preparation of 6-fluorobenzisothiazoles
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, (2008/06/13)
A process for the preparation of 6-fluoro-1,2-benzisothiazoles of formula I where R is hydrogen, loweralkyl, cycloalkyl, aralkyl, aryl, or a group of the formulae -CO2R2, -CN or -C(=O)R;2 R2 is alkyl or aryl; k,
Preparation of 6-fluorobenzisothiazoles via a regioselective nucleophilic aromatic substitution reaction
Fink,Strupczewski
, p. 6525 - 6528 (2007/10/02)
An efficient three step procedure for the preparation of 6-fluoro-1,2-benzisothiazoles is described. The key step is a regioselective nucleophilic aromatic substitution reaction in which the carbonyl group of a ketone or aldehyde directs nucleophilic disp
