150558-97-7

Upstream product

• 150560-30-8 methyl [2-(4-diphenylmethylpyrazol-1-yl)methyl-1,2,3,4-tetrahydronaphthalen-5-yloxy]acetate 
• 4279-81-6 3,3-diphenylpropanal 

Relevant academic research and scientific papers

Novel nonprostanoid prostacyclin (PGI2) mimetics with heterocyclic moiety

Structural modification of [2-(2-benzhydryloxyiminopentyl)-1,2,3,4-tetrahydro-5-naphthyloxy]acetic acid (4), previously identified as a PGI2 agonist without a PG skeleton, was examined. Conversion of the oxime moiety in 4 to the pyrazole led to [2-(4-benzhydrylpylazoyl)methyl-1,2,3,4-tetrahydro-5-naphthyloxy]acetic acid (34) which strongly inhibited ADP-induced aggregation of human platelets in vitro.

Fused benzeneoxyacetic acid derivatives

A fused benzeneoxyacetic acid derivative of the formula (I): STR1 R1 is OH, alkoxy, (alkyl)amino, residue of an amino acid; A is phenyl, alkyl substituted by phenyl, residue of an imidazole, imidazole-2-yloxy(thio), 2-oxoimidazole, pyrazole, ox