150592-48-6

Upstream product

• 67-56-1 methanol 
• 51295-68-2 3,4,6-tri-O-acetyl-β-D-galactopyranosyl chloride 
• 51295-69-3 3,4,6-tri-O-acetylα-D-galactopyranosyl chloride 
• 108-98-5 thiophenol 
• 3111-52-2 potassium thiophenolate 

Downstream Products

• 153439-89-5 Acetic acid (2R,3S,4S,5R,6S)-3-acetoxy-2-acetoxymethyl-5-(chloro-dimethyl-silanyloxy)-6-phenylsulfanyl-tetrahydro-pyran-4-yl ester 
• 150592-49-7 methyl 3-O-(3,4,6-tri-O-acetyl-α-D-galactopyranosyl)-2,4,6-tri-O-benzyl-α-D-glucopyranoside 
• 150592-53-3 methyl 2,6-di-O-benzyl-3-O-(3,4,6-tri-O-acetyl-α-D-galactopyranosyl)-α-D-glucopyranoside 

Relevant academic research and scientific papers

Synthesis and biological activity of α-galactosyl ceramide KRN7000 and galactosyl (α1→2) galactosyl ceramide

We herein report a faster and less cumbersome synthesis of the biologically attractive, α-galactosyl ceramide (α-GalCer), known as KRN7000, and its analogues. More importantly, the use of a silicon tethered intramolecular glycosylation reaction gave easy

Efficient stereocontrolled glycosidation of secondary sugar hydroxyls by silicon tethered intramolecular glycosidation

Dissaccharides containing 1,2-cis glycoside linkages were synthesized by an efficient stereocontrolled two step process involving a silicon tethering step, to a dimethylsilyl acetal followed by intramolecular glycosidation with N-iodosuccinimide in nitrom

Application of Intramolecular Glycosidation to the Stereocontrolled Synthesis of Disaccharides containing α-Gluco and α-Galacto Linkages

Disaccharides containing α-glucose and α-galactose linkages are stereospecifically synthesized from primary and secondary sugar hydroxy groups and a 2-hydroxythioglycoside via intramolecular glycosidation of a dimethylsilyl tethered intermediate.