150592-48-6Relevant articles and documents
Synthesis and biological activity of α-galactosyl ceramide KRN7000 and galactosyl (α1→2) galactosyl ceramide
Veerapen, Natacha,Brigl, Manfred,Garg, Salil,Cerundolo, Vincenzo,Cox, Liam R.,Brenner, Michael B.,Besra, Gurdyal S.
scheme or table, p. 4288 - 4291 (2010/04/26)
We herein report a faster and less cumbersome synthesis of the biologically attractive, α-galactosyl ceramide (α-GalCer), known as KRN7000, and its analogues. More importantly, the use of a silicon tethered intramolecular glycosylation reaction gave easy
Application of Intramolecular Glycosidation to the Stereocontrolled Synthesis of Disaccharides containing α-Gluco and α-Galacto Linkages
Bols, Mikael
, p. 791 - 792 (2007/10/02)
Disaccharides containing α-glucose and α-galactose linkages are stereospecifically synthesized from primary and secondary sugar hydroxy groups and a 2-hydroxythioglycoside via intramolecular glycosidation of a dimethylsilyl tethered intermediate.