150615-45-5

Basic information

• Product Name: (+)-(4S)-3-<(2'R)-2'-(hydroxymethyl)butanoyl>-4-benzyl-2-oxazolidinone
• Synonyms: (+)-(4S)-3-<(2'R)-2'-(hydroxymethyl)butanoyl>-4-benzyl-2-oxazolidinone
• CAS NO: 150615-45-5
• Molecular Weight: 277.32
• Mol File: 150615-45-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (+)-(4S)-3-<(2'R)-2'-(hydroxymethyl)butanoyl>-4-benzyl-2-oxazolidinone(CAS DataBase Reference)
• NIST Chemistry Reference: (+)-(4S)-3-<(2'R)-2'-(hydroxymethyl)butanoyl>-4-benzyl-2-oxazolidinone(150615-45-5)
• EPA Substance Registry System: (+)-(4S)-3-<(2'R)-2'-(hydroxymethyl)butanoyl>-4-benzyl-2-oxazolidinone(150615-45-5)

Safety Data

• Hazardous Substances Data: 150615-45-5(Hazardous Substances Data)

Upstream product

• 3587-60-8 Benzyloxymethyl chloride 
• 111292-87-6 (S)-4-benzyl-3-butyryloxazolidin-2-one 
• 163457-34-9 (+)-(4S)-3-<(2'R)-2'-((benzyloxy)methyl)butanoyl>-4-benzyl-2-oxazolidinone 
• 110-88-3 1,3,5-Trioxan 

Downstream Products

• 163457-37-2 (-)-p-fluorophenyl (2E)-4-<((2'R)-2'-((tert-butyldimethylsiloxy)methyl)butanoyl)oxy>-2-butenoate 
• 163457-38-3 (E)-4-((R)-2-Hydroxymethyl-butyryloxy)-but-2-enoic acid 4-fluoro-phenyl ester 
• 163457-29-2 (-)-p-fluorophenyl (2E)-4-<((2'R)-2'-(bromomethyl)butanoyl)oxy>-2-butenoate 
• 437985-97-2 (S)-4-Benzyl-3-{(R)-2-[diisopropyl-(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluoro-octyl)-silanyloxymethyl]-butyryl}-oxazolidin-2-one 
• 157405-12-4 (+)-(4S)-3-<(2'R)-2'-((tert-Butyldimethylsiloxy)methyl)butanoyl>-4-benzyl-2-oxazolidinone 

Relevant articles and documents

Total synthesis of (+)-spiculoic acid A

The total synthesis of natural (+)-spiculoic acid A, a new cytotoxic marine natural product of polyketide origin, has been accomplished for the first time. The key step of the total synthesis was a stereoselective and high-yielding intramolecular Diels-Alder reaction of a highly functionalized (E,E,E)-2,7,9-dodecanal derivative for the construction of the core tetrahydroindan-2-one skeleton.

Synthesis of six-membered compounds by environmentally friendly cyclization using indirect electrolysis

[Ni(cyclam)](ClO4)2-catalyzed indirect electroreduction of olefinic bromides produced six-membered compounds in low to high yields. The synthetic intermediate 49 of Ipecac and Corynanthe alkaloids was obtained in 88% yield in a highly stereoselective manner. Lactam 66, the synthetic precursor of tacamonine, was prepared in 49% yield as a mixture of two diastereoisomers. The electrolysis of the bromoacetates gave the debrominated compounds in good yields.