150618-13-6Relevant academic research and scientific papers
Stereospecific Synthesis of (2R,3S)-3-Amino-2-Piperidineacetic Acid Derivatives for Use as Conformational Constraint in Peptides
Gomez-Monterrey, Isabel,Gonzalez-Muniz, Rosario,Herranz, Rosario,Garcia-Lopez, Teresa
, p. 3593 - 3594 (1993)
Catalytic hydrogenation at 40 deg C of the β-ketoester, obtained from Boc-Orn(Z)-OH and ethyl lithioacetate, provides exclusively ethyl (2R,3S)-3-tert-butyloxycarbonylamino-2-piperidineacetic acid which when suitably protected can be used for peptide synthesis.
