150651-57-3Relevant academic research and scientific papers
PROCESS FOR THE PREPARATION OF SUVOREXANT AND INTERMEDIATES USEFUL IN THE SYNTHESIS OF SUVOREXANT
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Paragraph 0126-0127, (2016/07/05)
A novel processes for the preparation of suvorexant (formula I), its related compounds and its intermediates that are simple, economical and commercially viable. (I)
Synthesis of 2,3,6,7-Tetrahydro- and 2,3,4,5,6,7-Hexahydro-1H-1,4-diazepines via a Tandem Michael-type Addition-Intramolecular Aza-Wittig Sequence
Benalil, Aziza,Guerin, Andrea,Carboni, Bertrand,Vaultier, Michel
, p. 1061 - 1064 (2007/10/02)
Intramolecular aza-Wittig reaction of azides derived from 1,2-amino azides and α,β-unsaturated ketones leads to 2,3,6,7-tetrahydro-1H-1,4-diazepines.Reduction of these compounds with lithium aluminium hydride affords the corresponding saturated heterocycles.
