15068-99-2Relevant academic research and scientific papers
Perfluoroalkylsulfonyl fluoride in organic synthesis: a facile synthesis of 17α-hydroxy steroids
Guo, Peng-Peng,Ding, Kai
, p. 4096 - 4100 (2015)
Abstract A facile synthesis of 17α-hydroxy steroids with perfluoroalkylsulfonyl fluoride as hydroxyl activating agent was reported. The method features mild (40 °C), rapid (0.5 h), high yield, and high functional group tolerance. Notably, the method is applicable to HCOOH and CF3COOH, unusual and synthetically useful nucleophiles in hydroxyl inversion reaction.
