150715-15-4Relevant academic research and scientific papers
Jatrodien, a lignan from stems of Jatropha gossypifolia
Das, Biswanath,Rao, S. Padma,Srinivas,Das, Ratna
, p. 985 - 987 (1996)
A novel lignan, jatrodien, representing an intermediate in Haworth's biosynthetic scheme for the formation of lignans, has been isolated from the stems of Jatropha gossypifolia. The structure of the compound was derived from its spectroscopic data. Synthesis of the compound, starting from piperonal has been achieved. Copyright
Flow Photochemistry as a Tool for the Total Synthesis of (+)-Epigalcatin
Lisiecki, Kamil,Czarnocki, Zbigniew
, p. 605 - 607 (2018)
The first total synthesis of (+)-epigalcatin was completed in a highly stereoselective manner starting from piperonal, 3,4-dimethylbenzaldehyde, and diethyl succinate. l-Prolinol was used as a chiral auxiliary. The crucial step in this procedure involves
Efficient synthesis of lactonic and thionolactoniclignans and evaluation of their anti-oxidant, anti-inflammatory and cytotoxic activities
Golakoti, Trimurtulu,Kancharla, Hari Krishna,Meka, Bharani,Murthy
, p. 2906 - 2915 (2016/11/09)
A short and versatile synthesis of α,β-dibenzyl-γ-butyrolactones has been developed starting from inexpensive materials by applying Stobbe condensation and following the novel reductive cyclisation with sodiumborohydride. Natural products Suchilactone (5a
A convenient total synthesis of (+/-)-jatrophan and 2,3-bis-(hydroxymethyl)-6,7-methylenedioxy-1-(3',4'-dimethoxyphenyl)naphthalene, lignan constituents of Jatropha gossypifolia Linn.
Banerji, J,Bose, P,Chakrabarti, R,Das, B
, p. 709 - 712 (2007/10/02)
Convenient synthetic routes to (+/-)-jatrophan and 2,3-bis-(hydroxymethyl)-6,7-methylenedioxy-1-(3',4'-dimethoxyphenyl)naphthalene; the constituents of Jatropha gossypifolia Linn. have been reported.Stobbe condensation of piperonal with dimethyl succinate followed by methylation affords 4-(3',4'-methylenedioxyphenyl)-3-methoxy-carbonyl-methylbut-3-enoate.A second Stobbe condensation with veratraldehyde followed by Bouveault-Blanc reduction affords (+/-)-jatrophan.The aryl naphthalene lignan, 2,3-bis-(hydroxymethyl)-6,7-methylenedioxy-1-(3',4'-dimethoxyphenyl)naphthalene, has been synthesised from jatrophan by oxidative cyclisation followed by lithium aluminum hydride reduction.
