150725-87-4

Basic information

• Product Name: Ro 46-2005
• Synonyms: Ro 46-2005
• CAS NO: 150725-87-4
• Molecular Formula: C₂₃H₂₇N₃O₆S
• Molecular Weight: 473.547
• Mol File: 150725-87-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 617.5°C at 760 mmHg
• Flash Point: 327.3°C
• Appearance: /
• Density: 1.299g/cm³
• Vapor Pressure: 4.15E-16mmHg at 25°C
• Refractive Index: 1.592
• Storage Temp.: Sealed in dry,Store in freezer, under -20°C
• PKA: 0.83±0.10(Predicted)
• CAS DataBase Reference: Ro 46-2005(CAS DataBase Reference)
• NIST Chemistry Reference: Ro 46-2005(150725-87-4)
• EPA Substance Registry System: Ro 46-2005(150725-87-4)

Safety Data

• Hazardous Substances Data: 150725-87-4(Hazardous Substances Data)

Usage

Uses

RO462005 is an endothelin receptor selective agonist.

InChI:InChI=1/C23H27N3O6S/c1-23(2,3)16-8-10-19(11-9-16)33(28,29)26-21-20(22(25-15-24-21)31-13-12-27)32-18-7-5-6-17(14-18)30-4/h5-11,14-15,27H,12-13H2,1-4H3,(H,24,25,26)

Upstream product

• 150727-29-0 4-tert-butyl-N-{6-chloro-5-(3-methoxyphenoxy)pyrimidin-4-yl}benzenesulfonamide 

Downstream Products

• 169677-24-1 4-tert-butyl-N-(5-(3-methoxyphenoxy)-6-(2-((6-chloro-3-pyridazinyl)oxy)ethoxy)-4-pyrimidinyl)benzenesulfonamide 
• 167403-21-6 [2-[6-(4-tert-butyl-phenylsulfonylamino)-5-(3-methoxy-phenoxy)-pyrimidin-4-yloxy]-ethoxycarbonylamino]-acetic acid ethyl ester 

Relevant articles and documents

SULFONAMIDES

The novel sulfonamides of formula I, STR1 in which the symbols R. sup.1-R 9, R a, R b, X, Y and n have the significance given in the description and salts thereof can be used for the treatment of circulatory disorders, especially hypertension, ischemia, vasopasms and angina pectoris.