150749-03-4Relevant articles and documents
Synthesis of a naturally occurring diene-containing amino acid and its glutamyl dipeptide via N-acyliminium ion chemistry
Berkheij, Martin,Dijkink, Jan,David, Olivier R. P.,Sonke, Theo,Ijzendoorn, Denis R.,Blaauw, Richard H.,Van Maarseveen, Jan H.,Schoemaker, Hans E.,Hiemstra, Henk
experimental part, p. 914 - 924 (2009/04/11)
The syntheses of the naturally occurring unusual unsaturated amino acid (S)-2-amino-3-methylene-4-pentenoic acid and the corresponding γ-glutamyl dipeptide are described. Key steps are an N-acyliminium ion addition using allenylmethylsilane as nucleophile and an enzymatic resolution mediated by the L-aminopeptidase from Pseudomonas putida. Wiley-VCH Verlag GmbH & Co. KGaA, 2008.
Zinc mediated addition of active halides to a glycine cation equivalent: Synthesis of N-Boc-L-propargylglycine
Abood, Norman A.,Nosal, Roger
, p. 3669 - 3672 (2007/10/02)
The reaction of allylic, benzylic and propargylic halides with zine in the presence of the glycine cation equivalent, methyl N-Boc-2-acetoxyglycine, affords Boc protected amino acid derivatives in high yield. Resolution of methyl N-Boc- propargylglycine w