15082-28-7

Basic information

• Product Name: 2-(4-tert-Butylphenyl)-5-(4-biphenyl)-1,3,4-oxadiazole
• Synonyms: 1,3,4-Oxadiazole, 2-(4-biphenylyl)-5-(p-tert-butylphenyl)-;1,3,4-Oxadiazole, 2-[1,1'-biphenyl]-4-yl-5-[4-(1,1-dimethylethyl)phenyl]-;2-(t-Butylphenyl)-5-(4-biphenylyl)-1,3,4-oxadiazole;2-[1,1'-Biphenyl]-4-yl-5-(4-tert-butylphenyl)-1,3,4-oxadiazole;3,4-Oxadiazole,2-(1,1’-biphenyl)-4-yl-5-[4-(1,1-dimethylethyl)phenyl]-1;4-oxadiazole,2-[1,1’-biphenyl]-4-yl-5-[4-(1,1-dimethylethyl)phenyl]-3;LABOTEST-BB LT00441240;BUTYL-PBD
• CAS NO: 15082-28-7
• Molecular Formula: C₂₄H₂₂N₂O
• Molecular Weight: 354.45
• EINECS: 239-135-7
• Product Categories: Miscellaneous;Electroluminescence;Functional Materials;Highly Purified Reagents;Other Categories;Refined Products by Sublimation;White powder;oled materials
• Mol File: 15082-28-7.mol
• Article Data: 1

Chemical Properties

• Melting Point: 137-139 °C
• Boiling Point: 505.1 °C at 760 mmHg
• Flash Point: 244.9 °C
• Appearance: White powder
• Density: 1.103 g/cm³
• Vapor Pressure: 7.91E-10mmHg at 25°C
• Refractive Index: 1.579
• Storage Temp.: 2-8°C
• Solubility: toluene: 0.1 g/mL, clear, colorless
• PKA: -4.94±0.37(Predicted)
• BRN: 1086414
• CAS DataBase Reference: 2-(4-tert-Butylphenyl)-5-(4-biphenyl)-1,3,4-oxadiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-tert-Butylphenyl)-5-(4-biphenyl)-1,3,4-oxadiazole(15082-28-7)
• EPA Substance Registry System: 2-(4-tert-Butylphenyl)-5-(4-biphenyl)-1,3,4-oxadiazole(15082-28-7)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 20/21/22-36/37/38
• Safety Statements: 24/25-36-26
• WGK Germany: 3
• F: 8
• TSCA: Yes
• Hazardous Substances Data: 15082-28-7(Hazardous Substances Data)

Usage

Chemical Properties

white powder

InChI:InChI=1/C24H22N2O/c1-24(2,3)21-15-13-20(14-16-21)23-26-25-22(27-23)19-11-9-18(10-12-19)17-7-5-4-6-8-17/h4-16H,1-3H3

Upstream product

• 43100-38-5 4-tert-butylbenzoic acid hydrazide 
• 5449-21-8 2-([1,1’-biphenyl]-4-yl)-2-oxoacetic acid 

Downstream Products

• 85884-56-6 2-(4-(tert-butyl)phenyl)-5-(4'-vinyl-[1,1'-biphenyl]-4-yl)-2,5-dihydro-1,3,4-oxadiazole 
• 124454-24-6 2-[4-(4'-acetylbiphenylyl)]-5-(4-tert-butylphenyl)-1,3,4-oxadiazole 

Relevant articles and documents

Electrochemical Synthesis of 2,5-Disubstituted 1,3,4-Oxadiazoles from α-Keto Acids and Acylhydrazines Under Mild Conditions

1,3,4-Oxadiazoles are a kind of useful heterocycles which can be frequently found in materials and bioactive molecules. In this study, intermolecular electrochemical cyclization between α-keto acids and acylhydrazines has been developed for the synthesis of 2,5-disubstituted 1,3,4-oxadiazoles with the yield up to 91 %. This transformation can be run under mild reaction conditions in the absence of external oxidant, base and transition metal catalyst. Both symmetrical and unsymmetrical 2,5-disubstituted 1,3,4-oxadiazoles could be prepared according to the careful choice of the substrate combination. Gram scale synthesis also illustrates the potential application of this protocol in large preparation.