1508307-35-4Relevant academic research and scientific papers
Synthesis and structure-activity relationship of novel indole acrylamide derivatives as hcv replication inhibitors
Son, Seohyun,Kim, Dahee,Lee, Sungjin,Jin, Guanghai,Park, Jin-Ah,Han, Hyo-Kyung,Lee, Kyeong,Lee, Choongho
, p. 88 - 98 (2015/03/03)
Aseries of indole acrylamide derivatives were synthesized and evaluated for their inhibitory effects on hepatitis C virus (HCV) replication. Previously, we have identified (E)-N-(4- tert-butylphenyl)-3-(5-cyano-1H-indol-3-yl)-2-methylacrylamide (6c) as on
Chemical genetics-based discovery of indole derivatives as HCV NS5B polymerase inhibitors
Jin, Guanghai,Lee, Sungjin,Choi, Moonju,Son, Seohyun,Kim, Geon-Woo,Oh, Jong-Won,Lee, Choongho,Lee, Kyeong
, p. 413 - 425 (2014/03/21)
In order to identify the inhibitors of hepatitis C virus (HCV) replication with a novel scaffold via a mechanistically unbiased approach, we screened our in-house library composed of ~6000 compounds with various chemical structures by using the renilla lu
