1508307-36-5

Upstream product

• 1508307-11-6 (E)-ethyl 3-(5-cyano-1H-indol-3-yl)-2-methylacrylate 
• 17380-18-6 3-formyl-1H-indole-5-carbonitrile 
• 769-92-6 4-tert-Butylaniline 
• 1508307-22-9 (E)-3-(5-cyano-1H-indol-3-yl)-2-methylacrylic acid 

Relevant academic research and scientific papers

Synthesis and structure-activity relationship of novel indole acrylamide derivatives as hcv replication inhibitors

Aseries of indole acrylamide derivatives were synthesized and evaluated for their inhibitory effects on hepatitis C virus (HCV) replication. Previously, we have identified (E)-N-(4- tert-butylphenyl)-3-(5-cyano-1H-indol-3-yl)-2-methylacrylamide (6c) as on

Indole compound with selective inhibitory activity of genome replication of HCV, method for preparing the same, and pharmaceutical composition comprising the same for preventing or treating hepatitis C

The present invention relates to an indole based compound having a selective inhibiting activity on genome replication of the hepatitis C virus, a production method for same, and a pharmaceutical composition for preventing or treating hepatitis C containi

Chemical genetics-based discovery of indole derivatives as HCV NS5B polymerase inhibitors

In order to identify the inhibitors of hepatitis C virus (HCV) replication with a novel scaffold via a mechanistically unbiased approach, we screened our in-house library composed of ～6000 compounds with various chemical structures by using the renilla lu