1508318-85-1 Usage
Uses
Used in Pharmaceutical Industry:
(S)-4-benzyl-3-((R)-3-cyclopentyl-3-hydroxy-4-pentynoyl)oxazolidin-2-one is used as a key intermediate in the synthesis of novel pharmaceutical compounds due to its structural diversity and chirality. Its complex framework allows for the development of new drugs with potential applications in treating various diseases and conditions.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, (S)-4-benzyl-3-((R)-3-cyclopentyl-3-hydroxy-4-pentynoyl)oxazolidin-2-one serves as a valuable compound for studying the structure-activity relationships of biologically active molecules. Its unique structural features can be exploited to design and optimize new therapeutic agents with improved efficacy and selectivity.
Used in Drug Development:
(S)-4-benzyl-3-((R)-3-cyclopentyl-3-hydroxy-4-pentynoyl)oxazolidin-2-one is utilized in drug development as a starting material or a building block for creating innovative drug candidates. Its chiral nature and diverse functional groups enable the synthesis of enantiomerically pure compounds, which is crucial for the development of drugs with minimal side effects and high target specificity.
Overall, (S)-4-benzyl-3-((R)-3-cyclopentyl-3-hydroxy-4-pentynoyl)oxazolidin-2-one is a versatile and promising chemical entity with potential applications across various scientific and pharmaceutical fields, including pharmaceutical industry, medicinal chemistry research, and drug development. Its unique structural features and chirality make it an attractive candidate for the development of novel therapeutic agents and the advancement of our understanding of structure-activity relationships in biologically active molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 1508318-85-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,5,0,8,3,1 and 8 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1508318-85:
(9*1)+(8*5)+(7*0)+(6*8)+(5*3)+(4*1)+(3*8)+(2*8)+(1*5)=161
161 % 10 = 1
So 1508318-85-1 is a valid CAS Registry Number.
1508318-85-1Relevant academic research and scientific papers
Synthesis of filibuvir. Part I. Diastereoselective preparation of a β-hydroxy alkynyl oxazolidinone and conversion to a 6,6- disubstituted 2H-pyranone
Singer, Robert A.,Ragan, John A.,Bowles, Paul,Chisowa, Esmort,Conway, Brian G.,Cordi, Eric M.,Leeman, Kyle R.,Letendre, Leo J.,Sieser, Janice E.,Sluggett, Gregory W.,Stanchina, Corey L.,Strohmeyer, Holly,Blunt, Jon,Taylor, Stuart,Byrne, Ciaran,Lynch, Denis,Mullane, Sandra,O'Sullivan, Maria M.,Whelan, Marcella
, p. 26 - 35 (2014/05/20)
This is the first in a series of three papers describing the identification and development of a commercial synthesis of filibuvir (1). This contribution describes development of an Evans aldol reaction to control the tertiary alcohol stereocenter, a challenging variant of that strategy in that both reacting partners were nonstandard (acetate enolate and ketone electrophile). A sequence consisting of Sonogashira coupling, acylation and hydrogenation delivered acetate 24, and Dieckmann cyclization provided β-keto lactone 2.
