150851-98-2

Basic information

• Product Name: (1S,4R)-5-benzyl-5-azabicyclo[2.2.1]hept-2-ene
• Synonyms: 2-Azabicyclo[2.2.1]hept-5-ene, 2-(phenylmethyl)-, (1R,4S)-
• CAS NO: 150851-98-2
• Molecular Formula: C13H15N
• Molecular Weight: 185.2649
• Mol File: 150851-98-2.mol
• Article Data: 18

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (1S,4R)-5-benzyl-5-azabicyclo[2.2.1]hept-2-ene(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,4R)-5-benzyl-5-azabicyclo[2.2.1]hept-2-ene(150851-98-2)
• EPA Substance Registry System: (1S,4R)-5-benzyl-5-azabicyclo[2.2.1]hept-2-ene(150851-98-2)

Safety Data

• Hazardous Substances Data: 150851-98-2(Hazardous Substances Data)

Usage

General Description

(1S,4R)-5-benzyl-5-azabicyclo[2.2.1]hept-2-ene is a chemical compound that belongs to the class of bicyclic compounds. It is specifically categorized as a bicyclic amine and contains a benzene ring substitution. (1S,4R)-5-benzyl-5-azabicyclo[2.2.1]hept-2-ene has a stereocenter at the 1 and 4 positions, with the (1S,4R) configuration. The chemical structure of (1S,4R)-5-benzyl-5-azabicyclo[2.2.1]hept-2-ene imparts unique characteristics and reactivity, making it suitable for use in organic synthesis and medicinal chemistry. It may also have potential applications in pharmaceuticals or as a building block in the synthesis of complex molecules. Overall, (1S,4R)-5-benzyl-5-azabicyclo[2.2.1]hept-2-ene is a valuable chemical compound with diverse potential applications in the scientific and industrial fields.

Upstream product

• 50-00-0 formaldehyd 
• 3287-99-8 benzylamine hydrochloride 
• 542-92-7 cyclopenta-1,3-diene 
• 100-46-9 benzylamine 
• 100-39-0 benzyl bromide 
• 130931-83-8 (1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one 

Downstream Products

• 128862-57-7 N-benzyl-4,4-diphenyl-1,2,4,4a,7,7a-hexahydrocyclopenta-pyridin-3-one 

Relevant articles and documents

RuO4-catalyzed oxidation reactions of isoxazolino-2- azanorbornane derivatives: A short-cut synthesis of tricyclic lactams and peptidomimetic γ-amino acids

A rapid access to peptidomimetic conformationally constrained γ-amino acids has been developed through the efficient RuO4-mediated oxidation of regioisomeric isoxazolino-2-azanorbornane derivatives. The key intermediates are tricyclic lactams,

Isoxazoline-carbocyclic aminols for nucleoside synthesis through aza-Diels-Alder reactions

A novel approach to useful aminols for the synthesis of carbocyclic nucleosides is reported starting from a convenient source, the 2-azanorborn-5-enes. These are readily available through the Grieco cycloaddition of cyclopentadiene with iminium salts and

SUBSTITUTED 2-AZABICYCLES AND THEIR USE AS OREXIN RECEPTOR MODULATORS

The present invention is directed to compounds of Formula I: wherein X is N or CR1; Y is N or CR2; R1 is H, alkoxy, halo, triazolyl, pyrimidinyl, oxazolyl, isoxazole, oxadiazolyl, or pyrazolyl; R2 is H, alkyl, alkoxy, or halo; Z is NH or O; R3 is H, alkyl, alkoxy, halo, or triazolyl; R4 is H or alkyl; or R3 and R4, together with the atoms to which they are attached, form a 6-membered aryl ring or a 5- or 6-membered heteroaryl ring; R5 is pyridyl, pyrazinyl, or pyrimidinyl, wherein the pyridyl, pyrazinyl, or pyrimidinyl is optionally substituted with halo or alkyl; and n is 1 or 2. Methods of making the compounds of Formula I are also described. The invention also relates to pharmaceutical compositions comprising compounds of Formula I. Methods of using the compounds of the invention are also within the scope of the invention.