15104-41-3Relevant articles and documents
Arylphosphonate-Directed Ortho C-H Borylation: Rapid Entry into Highly-Substituted Phosphoarenes
Xu, Feiyang,Duke, Olivia M.,Rojas, Daniel,Eichelberger, Hanka M.,Kim, Raphael S.,Clark, Timothy B.,Watson, Donald A.
, p. 11988 - 11992 (2020)
Phosphonate-directed ortho C-H borylation of aromatic phosphonates is reported. Using simple starting materials and commercially accessible catalysts, this method provides steady access to o-phosphonate arylboronic esters bearing pendant functionality and flexible substitution patterns. These products serve as flexible precursors for a variety of highly substituted phosphoarenes, and in situ downstream functionalization of the products is described.
PHENYLPYRROLIDINONE FORMYL PEPTIDE 2 RECEPTOR AGONISTS
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Paragraph 0273; 0274, (2019/09/16)
The disclosure relates to compounds of Formulae (I)-(IX), which are formyl peptide 2 (FPR2) receptor agonists and/or formyl peptide 1 (FPR1) receptor agonists. The disclosure also provides compositions and methods of using the compounds, for example, for the treatment of atherosclerosis, heart failure, chronic obstructive pulmonary disease (COPD), and related diseases.