15107-41-2

Usage

Chemical Class

Chloroalkylbenzenes

Molecular Weight

242.73 g/mol

Physical State

Colorless to pale yellow liquid at room temperature

Solubility

Insoluble in water

Uses

Mainly used as a reagent in organic synthesis and chemical research

Potential Applications

Pharmaceutical and agrochemical industries, as well as in the production of various specialty chemicals

Safety Precautions

Handle with care and follow proper safety precautions to avoid health and environmental hazards.

Upstream product

• 2746-25-0 p-Methoxybenzyl bromide 
• 106-39-8 bromochlorobenzene 
• 5107-52-8 2-(p-methoxyphenyl)ethyl toluene-p-sulphonate 
• 702-23-8 2-(4-Methoxyphenyl)ethanol 
• 1073-67-2 4-vinylbenzyl chloride 
• 66107-29-7 4-methoxyphenyl triflate 
• 696-62-8 para-iodoanisole 
• 202145-29-7 N-(4-chlorobenzyl)-1-(4-methoxyphenyl)methanamine 
• 104-83-6 1-Chloro-4-(chloromethyl)benzene 
• 1530-39-8 (4-chlorobenzyl)triphenylphosphonium chloride 
• 15107-36-5 Triphenyl-<1-(4-chlor-phenyl)-2-(4-methoxyphenyl)-aethyl>-phosphoniumbromid 

Relevant academic research and scientific papers

Nickel-Catalyzed Regiodivergent Reductive Hydroarylation of Styrenes

We report a ligand-controlled nickel-catalyzed reductive hydroarylation of styrenes with predictable and controllable regioselectivity. With a diamine ligand, the reaction produces selective linear hydroarylation products. Alternatively, with a chiral PyrOx ligand, branch-selective enantioenriched 1,1-diarylalkane products are obtained. Preliminary mechanistic results are consistent with a reductive Heck process.

Copper-Catalyzed Radical Reductive Arylation of Styrenes with Aryl Iodides Mediated by Zinc in Water

A copper/aniline catalyst system enables the radical arylation of styrenes using aryl iodides mediated by zinc in water. This transformation provides an efficient synthetic methodology for the convenient synthesis of diarylethane.

Thermal Rearrangement of Sulfamoyl Azides: Reactivity and Mechanistic Study

The rearrangement of sulfamoyl azides under thermal conditions to form a C-C bond while breaking two C-N bonds is reported. Mechanistic study shows that this reaction goes through a Curtius-type rearrangement to form a 1,1-diazene, then which rearranges possibly through both a concerted rearrangement process and a stepwise radical process. This rearrangement could be used in the synthesis of complex biologically active molecules, such as sterols, and piperine derivatives.

Copper-Catalyzed Reductive Cross-Coupling of Nonactivated Alkyl Tosylates and Mesylates with Alkyl and Aryl Bromides

A copper-catalyzed reductive cross-coupling reaction of nonactivated alkyl tosylates and mesylates with alkyl and aryl bromides was developed. It provides a practical method for efficient and cost-effective construction of aryl-alkyl and alkyl-alkyl C=C bonds with stereocontrol from readily available substrates. When used in an intramolecular fashion, the reaction enables convenient access to various substituted carbo- or heterocycles, such as 2,3-dihydrobenzofuran and benzochromene derivatives.