151075-94-4Relevant academic research and scientific papers
Synthesis of (α,α-Difluoroalkyl)phosphonates by Displacement of Primary Triflates
Berkowitz, David B.,Eggen, MariJean,Shen, Quanrong,Sloss, Darby G.
, p. 6174 - 6176 (1993)
Simple primary alkyl triflates and those derived from several monosaccharides are cleanly displaced by diethyl(lithiodifluoromethyl)phosphonate to provide the corresponding (α,α-difluoroalkyl)phosphonates in minutes at -78 deg C.
Displacement of sugar triflates with C-nucleophiles: D-glucopyranose and D-ribofuranose chain extension and functionalization
Shen,Sloss,Berkowitz
, p. 1519 - 1530 (2007/10/02)
Treatment of methyl 4-O-benzyl-2,3-di-O-methoxymethyl-6-O- trifluoromethanesulfonyl-α-D-glucopyranoside 1 or 3-O-benzyl-1,2-O- isopropylidene-5-O-trifluoromethenesulfonyl-α-D-ribofuranoside 2 with a variety of functionalized C-nucleophiles in THF-HMPA lea
