151145-82-3Relevant academic research and scientific papers
TSAO derivatives: Highly specific inhibitors of human immunodeficiency virus type-1 (HIV-1) replication
Camarasa,Perez-Perez,Velazquez,San-Felix,Alvarez,Ingate,Jimeno,Karlsson,De Clercq,Balzarini
, p. 585 - 594 (2007/10/02)
TSAO derivatives represent a unique class of nucleosides that are specifically targeted at HIV-1 RT. This overview is focussed on the chemical synthesis, the conformational studies, the antiviral and metabolic properties of TSAO derivatives, as well as th
TSAO Analogues. 3. Synthesis and Anti-HIV-1 Activity of 2',5'-Bis-O-(tert-butyldimethylsilyl)-β-D-ribofuranosyl 3'-Spiro-5''-(4''-amino-1'',2''-oxathiole 2'',2''-dioxide) Purine and Purine-Modified Nucleosides
Velazquez, Sonsoles,San-Felix, Ana,Perez-Perez, Maria Jesus,Balzarini, Jan,Clercq, Erik De,Camarasa, Maria Jose
, p. 3230 - 3239 (2007/10/02)
Several purine and purine-modified analogues of the new lead anti-HIV-1 agent thymine>-3'-spiro-5''-(4''-amino-1'',2''-oxathiole 2'',2''-dioxide)(TSAO-T) have been prepared and evaluated as inhibit
