151215-43-9Relevant articles and documents
Synthesis, anti-HIV-1 activity, and modeling studies of N-3 Boc TSAO compound
Tomassi, Cyrille,Van Nhien, Albert Nguyen,Marco-Contelles, Jose,Balzarini, Jan,Pannecouque, Christophe,De Clercq, Erik,Soriano, Elena,Postel, Denis
, p. 2277 - 2281 (2008/09/21)
The synthesis and the biological evaluation of the anti-HIV-1 activity of TSAO-Boc3T (8) are described. The computational analysis showed that the N-3 Boc group promotes new interactions in the binding site of the enzyme leading to a good inhib