15121-74-1Relevant academic research and scientific papers
Photoinduced Deaminative Alkylation for the Synthesis of γ-Ketoesters via Electron Donor–Acceptor Complex Formation
Wang, Jia-Xin,Ge, Wei,Xing, Wei-Long,Fu, Ming-Chen
, p. 18224 - 18231 (2021/12/13)
Visible-light-induced deaminative alkylation of Katritzky salts with silyl enol ethers has been developed. The reaction can proceed efficiently through electron donor–acceptor complex formation, avoiding the use of precious metal complexes or synthetically elaborate organic dyes. A series of functionalized γ-ketoesters was successfully obtained with good functional group tolerance and compatibility under mild and straightforward conditions.
Isothiourea-catalyzed asymmetric O- to C-carboxyl transfer of furanyl carbonates
Joannesse, Caroline,Morrill, Louis C.,Campbell, Craig D.,Slawin, Alexandra M. Z.,Smith, Andrew D.
, p. 1865 - 1879 (2011/08/05)
The ability of a chiral isothiourea to promote the regio- and enantioselective O- to C-carboxyl transfer of a series of 3-alkyl-5-aryl- and 5-methyl-3-phenylfuranyl carbonates is examined, generating preferentially the -regioisomers (α/γ up to 83:17) with high asymmetric induction (up to 83% ee). Georg Thieme Verlag Stuttgart - New York.
Antihypertensive Agents: Angiotensin Converting Enzyme Inhibitors. 1--L-prolines
McEvoy, Francis J.,Lai, Fong M.,Albright, J. Donald
, p. 381 - 392 (2007/10/02)
A series of 1--L-proline derivatives was synthesized.A number of these compounds are potent angiotensin converting enzyme (ACE) inhibitors that lowered blood pressure in aorta-coarcted renal hypertensive rats.The most active
[4R]-3-(Omega-AROYLPROPIONYL)-4-THIAZOLIDINECARBOXYLIC ACIDS AND ESTERS
-
, (2008/06/13)
This disclosure describes novel 4R!-3-(ω-aroylpropionyl)-4-thiazolidinecarboxylic acids and esters and the cationic salts thereof which are useful as hypotensive agents in mammals.
