151223-08-4Relevant academic research and scientific papers
Synthesis of fluorinated acyclic nucleoside phosphonates with 5-azacytosine base moiety
Pomeisl, Karel,Kre?merová, Marcela,Pohl, Radek,Snoeck, Robert,Andrei, Graciela
, (2019/08/27)
With respect to the strong antiviral activity of (S)-1-[3-hydroxy-2-(phosphonomethoxy)propyl]-5-azacytosine various types of its side chain fluorinated analogues were prepared. The title compound, (S)-1-[3-fluoro-2-(phosphonomethoxy)propyl]-5-azacytosine
Synthesis and antiviral activity of 2'-substituted 9-[2- (phosphonomethoxy)ethyl]guanine analogues
Yu,Bronson,Yang,Patick,Alam,Brankovan,Datema,Hitchcock,Martin
, p. 2726 - 2738 (2007/10/02)
A series of 2'-substituted derivatives of 9-[2- (phosphonomethoxy)ethyl]guanine (PMEG, 1) have been synthesized and evaluated in vitro for anti-human immunodeficiency virus (HIV) activity in the XTT assay and for anti-herpes activity in the plaque reducti
