151262-57-6 Usage
Uses
3-[(4-Fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanoic Acid is an impurity of Bicalutamide (B382000); a non-steroidal peripherally active antiandrogen. Also used as an antineoplastic (hormonal).
Check Digit Verification of cas no
The CAS Registry Mumber 151262-57-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,1,2,6 and 2 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 151262-57:
(8*1)+(7*5)+(6*1)+(5*2)+(4*6)+(3*2)+(2*5)+(1*7)=106
106 % 10 = 6
So 151262-57-6 is a valid CAS Registry Number.
InChI:InChI=1/C10H11FO5S/c1-10(14,9(12)13)6-17(15,16)8-4-2-7(11)3-5-8/h2-5,14H,6H2,1H3,(H,12,13)
151262-57-6Relevant articles and documents
Palladium-catalyzed substitution of allylic alcohols with sulfinate salts: A synthesis of bicalutamide
Jhang, Yin-Jia,Chang, Chieh-Yu,Lin, Yu-Huan,Lee, Chein-Chung,Wu, Yen-Ku
, (2021/05/04)
A method is presented for the direct substitution of allylic alcohols with sodium arylsulfinates. The process involves a cooperative action of palladium catalysts, phenylboronic acid and titanium tetraisopropoxide. By taking advantage of this protocol, we achieved a concise synthesis of bicalutamide, an anti-androgen compound for treating prostate cancer.
