15131-72-3Relevant academic research and scientific papers
Synthesis of cholesteryl esters of heterocyclic analogs of cinnamic acid and hetaroyloxycinnamic acids by the Wittig reaction
Listvan,Listvan,Shekel'
, p. 1480 - 1483 (2002)
The reaction of cholesteryl triphenylphosphonioacetate chloride with heterocyclic aldehydes and hetaroyloxyarenecarbaldehydes in the presence of base gave the corresponding cholesteryl esters of substituted propenoic acids possessing liquid crystal proper
A compound and its preparation method and application
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Paragraph 0068; 0069; 0071, (2017/03/22)
The present invention relates to the field of drug synthesis, and discloses a compound, a preparation method and applications thereof. According to the present invention, the compound has the structure represented by a formula I or formula II, wherein RB is a compound residue having biological activity; the preparation method of the compound represented by the formula I or formula II has characteristics of easy performing, good reproducibility and low environmental pollution, and can be used for large scale preparation of the compound represented by the formula I or formula II; and the compound represented by the formula I or formula II is the compound having the completely-new structure, has effects of significant vasodilatation, anticoagulation and anti-ischemia-reperfusion injury, and can be used for preparation of drugs for prevention or treatment of cardiovascular and cerebrovascular diseases and anticoagulation drugs. The formula I and the formula II are defined in the instruction.
