10400-19-8Relevant academic research and scientific papers
Catalytic and electrocatalytic wet oxidation of phenol using two new nickel(II) tetraazamacrocycle complexes under heterogeneous conditions
Bansal, Vipin Kumar,Thankachan, Pompozhi Protasis,Prasad, Rajendra
, p. 131 - 138 (2010)
Two new tetraazamacrocycle complexes, namely, 7,16-dinicotinoyl[Ni{Me4(4-MeBzo)2[14]tetraeneN4}] and 7,16-diisonicotinoyl[Ni{Me4(4-MeBzo)2[14]tetraeneN4}] (where [Ni{Me4(4-MeBzo)
Palladium(II)-catalysed oxidation of alcohols under an oxygen atmosphere in a fluorous biphase system (FBS)
Nishimura, Takahiro,Maeda, Yasunari,Kakiuchi, Nobuyuki,Uemura, Sakae
, p. 4301 - 4305 (2000)
Palladium(II) acetate catalyses the aerobic oxidation of alcohols into the corresponding aldehydes and ketones in the presence of a catalytic amount of a novel perfluoroalkylated-pyridine as a ligand using molecular oxygen in a fluorous biphase system (FBS) composed of toluene and perfluorodecalin. This catalytic system is applicable to various benzylic and aliphatic alcohols. The fluorous phase containing the active palladium species is easily separated and can be reused several times without a significant loss of catalytic activity. The Royal Society of Chemistry 2000.
The bilateral action between EQ14-2-14 gemini surfactant and bovine serum albumin by DPI and 1H NMR
Wu, Gang,Jiang, Xiaohui,Zhou, Limei,Yang, Lijun,Wang, Ya,Xia, Guangqiang,Chen, Zhengjun,Duan, Ming
, p. 47 - 54 (2013)
Gemini surfactant diglycol bis-N-tetradecyl nicotinate dibromide (designed as EQ14-2-14) has been synthesized. The interaction between EQ14-2-14 and bovine serum albumin (BSA) was studied by dual polarization interferometry (DPI), proton nuclear magnetic resonance spectroscopy (1H NMR), Fourier transform infrared spectroscopy (FTIR) and molecular docking. Owing to the binding of EQ14-2-14, the thickness and mass of BSA increased; refractive index (RI) and density firstly raised and then tended to a plateau. In addition, a decrease of α-helix was observed from 54.01% to 31.56% with an increase in random structure from 7.86% to 21.76%. Due to BSA intertwining, the proton resonance signals of EQ14-2-14 shifted up-field and relaxation time decreased with increasing concentration of BSA. The study of molecular docking indicated that EQ14-2-14 embedded into subdomain II of BSA by π-π stacking between the electron-deficit pyridinium rings in EQ14-2-14 and the electron-abundant pyrrole ring in Trp residues of BSA, by hydrogen bonding and by hydrophobic interaction. Therefore the present work offers a whole view of the interaction of BSA with a new gemini surfactant.
Crystal structure and energy optimization of dichlorobis(ethylanthranilatonicotinamide)zinc(II)
Narayanan, Venkatraj V.,Gopalan, R. Srinivasa,Chakrabarty, Debojit,Mobin, Shaikh M.,Mathur, Pradeep
, p. 801 - 805 (2011)
The title compound, C30H28Cl2N 4O6Zn, dichlorobis(ethylanthranilatonicotinamide)zinc(II) crystallized in a triclinic space group, P - 1, with cell parameters a = 7.787(3), b = 13.468(1), c = 15.735(1)
Synthesis and characterization of novel 6-fluoro-4-piperidinyl-1,2- benzisoxazole amides and 6-fluoro-chroman-2-carboxamides: Antimicrobial studies
Priya,Basappa,Swamy, S. Nanjunda,Rangappa, Kanchugarakoppal S.
, p. 2623 - 2628 (2005)
Novel derivatives of 6-fluoro-4-piperidinyl-1,2-benzisoxazole amides 4(I-VI) were obtained by the condensation of different acid chlorides with 6-fluoro-3-piperidin-4yl-benzo[d]isoxazole. Also, 6-fluoro-chroman-2- carboxamides 6(I-III) were synthesized by using nebulic acid chloride with different amines in presence of triethylamine as acid scavenger and dichloroethane as solvent. The synthesized compounds were characterized by IR, 1H NMR, and CHN analysis. These molecules were evaluated for their efficacy as antimicrobials in vitro by disc diffusion and microdilution method against pathogenic strains such as Bacillus substilis, Escherichia coli, Pseudomonas fluorescens, Xanthomonas campestris pvs, X. oryzae, Aspergillus niger, A. flavus, Fusarium oxysporum, Trichoderma species, F. monaliforme, and Penicillum species. Compounds 4I, 4IV, 4V, 6I, 6II and 6III showed better inhibitory activity than compared to standard drugs. Among these compounds, 4IV and 6III showed potent inhibitory activity against all the strains and found to be nonstrain dependent. The title compounds represent a novel class of potent antimicrobial agents.
Anion templated surface assembly of a redox-active sensory rotaxane
Bayly, Simon R.,Gray, Thomas M.,Chmielewski, Michal J.,Davis, Jason J.,Beer, Paul D.
, p. 2234 - 2236 (2007)
Anion templation is used to assemble novel redox-active bis-ferrocene functionalised rotaxane self-assembled monolayers (SAMs) on to gold electrode surfaces; after template removal, the unique SAM rotaxane binding domain is capable of selectively sensing chloride ions electrochemically. The Royal Society of Chemistry.
One-pot preparation of esters from carboxylic acids using the PPh3-CCl3CN system
Jang, Doo Ok,Cho, Dae Hyan,Kim, Joong-Gon
, p. 2885 - 2890 (2003)
A convenient one-pot process for preparing various esters from carboxylic acids using the Ph3P-CCl3CN has been developed. Racemic α-tocopherol, clofibrate and flavoxate were prepared in high yields using this method.
Fluorescent hydrogels formed by CH-π and π-π Interactions as the main driving forces: An approach toward understanding the relationship between fluorescence and structure
Ahn, Jinho,Park, Sunhong,Lee, Ji Ha,Jung, Sung Ho,Moon, Seung-Jin,Jung, Jong Hwa
, p. 2109 - 2111 (2013)
Amide-linked tripyridine derivatives 1, with a para-substituent, and 2, with a meta-substituent, were gelated in water or water-DMSO. The gelation capabilities of 1 and 2 were attributed to the cooperative effects of mainly CH-π and π-π stacking or strong intermolecular hydrogen bonding interactions between the amide groups. The fluorescence properties of gels 1 and 2 were dependent on the binding strength of the π-π stacking.
Lipid lowering activity of novel N-(benzoylphenyl)pyridine-3-carboxamide derivatives in Triton WR-1339-induced hyperlipidemic rats
Abu Farha, Rana,Bustanji, Yasser,Al-Hiari, Yusuf,Al-Qirim, Tariq,Abu Shiekha, Ghassan,Albashiti, Rabab
, p. 138 - 144 (2016)
Context: Dyslipidemia is a major risk factor for the development of cardiovascular diseases. Many dyslipidemic patients do not achieve their target lipid levels with the currently available medications, and most of them may experience many side effects. Objective: The present work aimed toward identifying a new class of novel nicotinic acid-carboxamide derivatives as promising antihyperlipidemic compounds. Materials and methods: Six novel N-(benzoylphenyl)pyridine-3-carboxamide derivatives were synthesized using acid chloride pathways. All structures were confirmed using 1H-NMR, 13C-NMR, IR, and HRMS. The evaluation of biological activity was conducted using Triton WR-1339-induced hyperlipidemic rats model. Results: This study revealed that some of the newly synthesized novel N-(benzoylphenyl)pyridine-3-carboxamide derivatives mainly C4 and C6 possessed significant antihyperlipidemic activities on lipid components TG and TC (p value 0.05). Discussion and conclusion: This research opens the door for new potential antihyperlipidemic compounds derived from nicotinic acid that need further optimization of their biological activities.
Polymeric complexes with "piperazine-pyridine" building blocks: Synthesis, network structures, and third-order nonlinear optical properties
Hou, Hongwei,Song, Yinglin,Xu, Hong,Wei, Yongli,Fan, Yaoting,Zhu, Yu,Li, Linke,Du, Chenxia
, p. 999 - 1008 (2003)
A new bidentate "building block", N,N′-bis(3-pyridylformyl)piperazine (bpfp), was synthesized. X-ray diffraction studies reveal that the piperazine ring in bpfp forms a chairlike structure conformation, bpfp self-assembled into two-dimensional layered rhombohedral grid polymers {[Mn(H2O)2(SO4)(bpfp)](H2O)3 (CH3OH)}n (1) and {[Zn(NCS)2(bpfp)2]·2H2O}n (2) with Mn(II) and Zn(II), a three-dimensional polymer [Cd(N3)2(bpfp)]n (3) with Cd(II), and a one-dimensional zigzag polymer [HgI2(bpfp)]n (4) with Hg(II). Each rhombohedral grid in polymer 1 is composed of four Mn, two bpfp, and two SO42-; the dimensions of the grid are 6.537 × 12.843 A. In polymer 2, each rhombohedral grid consists of 60-membered rings Zn4(bpfp)4 showing the dimensions of 14.231 × 15.586 A. Zn4(bpfp)4 grids are bridged by Zn ions and all pyridyl-N atoms of bpfp ligands into the 2-D network structure along a and c directions. Polymer 3 exhibits a 3-D layered structure with tetragonal prism channel viewing from a direction. The bpfp ligands occupy the four edges of tetragonal prism channel, which is cut off by layers consisting of rhombohedral grids Cd4(N3)4. Polymer 4 is quite different from polymers 1-3; it exhibits a 1-D zigzag framework extending along the c axis. Polymers 1-3 possess a very strong NLO absorption and self-focusing effect. Their third-order NLO absorptive coefficients α2 are 9.2 × 10-9, 6.9 × 10-9, and 7.1 × 10-9 m W-1. The third-order NLO hyperpolarizabilities γ are 1.79 × 10-28, 9.10 × 10-29, and 9.66 × 10-29 esu, respectively. The γ values are comparable to those of the best NLO materials and coordination polymers. We found that the valence shell structures of central metal ions can influence the NLO properties of coordination polymers.
