151331-95-2Relevant academic research and scientific papers
Structure-Based Design of Inhibitors of Purine Nucleoside Phosphorylase. 3. 9-Arylmethyl Derivatives of 9-Deazaguanine Substituted on the Methylene Group
Erion, Mark D.,Niwas, Shri,Rose, Jerry D.,Ananthan, Subramaniam,Allen, Mark,et al.
, p. 3771 - 3783 (2007/10/02)
X-ray crystallography and computer-assisted molecular modeling (CAMM) studies aided in the design of a potent series of Mammalian purine nucleoside phosphorylase (PNP) inhibitors.Enhanced potency was achieved by designing substituted 9-(arylmethyl)-9-deaz
