1513846-41-7Relevant academic research and scientific papers
Asymmetric homoenolate additions to acyl phosphonates through rational design of a tailored N-heterocyclic carbene catalyst
Jang, Ki Po,Hutson, Gerri E.,Johnston, Ryne C.,McCusker, Elizabeth O.,Cheong, Paul H.-Y.,Scheidt, Karl A.
, p. 76 - 79 (2014)
A highly selective NHC-catalyzed synthesis of γ-butyrolactones from the fusion of enals and α-ketophosphonates has been developed. Computational modeling of competing transition states guided a rational design strategy to achieve enhanced levels of enanti
