151386-97-9Relevant academic research and scientific papers
Synthesis and SAR of new 5-phenyl-3-ureido-1,5-benzodiazephines as cholecystokinin-B receptor antagonists
Ursini,Capelli,Carr,Cassarà,Corsi,Curcuruto,Curotto,Dal Cin,Davalli,Donati,Feriani,Finch,Finizia,Gaviraghi,Marien,Pentassuglia,Polinelli,Ratti,Reggiani,Tarzia,Tedesco,Tranquillini,Trist,Van Amsterdam
, p. 3596 - 3613 (2007/10/03)
A series of 5-phenyl-3-ureidobenzodiazepine-2,4-diones was synthesized and evaluated as cholecystokinin-B (CCK-B) receptor antagonists. Structure-activity relationship (SAR) studies revealed the importance of the N-1 substituent for potent and selective C
1,5-benzodiazepine derivatives
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, (2008/06/13)
The present invention relates to compounds of formula (I) which are antagonists of gastrin and CCK-B receptors. The compounds of formula (I) are 1,5-benzodiazepine derivatives. STR1
