151390-97-5

Basic information

• Product Name: 2'-O-Propargyladenosine
• Synonyms: 2'-O-Propargyladenosine;2'-O-(2-Propyn-1-yl)adenosine
• CAS NO: 151390-97-5
• Molecular Formula: C₁₃H₁₅N₅O₄
• Molecular Weight: 305.29
• Mol File: 151390-97-5.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 655.1±65.0 °C(Predicted)
• Appearance: /
• Density: 1.65±0.1 g/cm3(Predicted)
• PKA: 13.00±0.70(Predicted)
• CAS DataBase Reference: 2'-O-Propargyladenosine(CAS DataBase Reference)
• NIST Chemistry Reference: 2'-O-Propargyladenosine(151390-97-5)
• EPA Substance Registry System: 2'-O-Propargyladenosine(151390-97-5)

Safety Data

• Hazardous Substances Data: 151390-97-5(Hazardous Substances Data)

Usage

General Description

2'-O-Propargyladenosine is a modified nucleoside that contains a propargyl group attached to the 2' position of the ribose ring of adenosine. This chemical modification can have a significant impact on the properties and functions of adenosine in biological systems. 2'-O-Propargyladenosine can be used as a substrate for enzymes such as adenosine deaminase, and it has been investigated for its potential use in the development of new therapeutic agents. Additionally, this modified nucleoside has been explored for its potential applications in bioconjugation and click chemistry reactions, as the propargyl group can participate in copper-catalyzed azide-alkyne cycloaddition reactions. Overall, 2'-O-Propargyladenosine is a versatile chemical compound with potential applications in both biological and chemical research.

Upstream product

• 106-96-7 propargyl bromide 
• 58-61-7 adenosine 

Downstream Products

• 1282033-18-4 2'-O-(3-(furan-2-yl)-propyn-3-yl)-6-N-benzoyladenosine 
• 1282033-19-5 2'-O-(3-(furan-2-yl)-propyl)-6-N-benzoyladenosine 
• 1282033-20-8 5'-O-(4,4'-dimethoxytriphenylmethyl)-2'-O-(3-(furan-2-yl)-propyl)-6-N-benzoyladenosine 
• 1282033-21-9 5'-O-(4,4'-dimethoxytriphenylmethyl)-2'-O-(3-(furan-2-yl)-propyl)-6-N-benzoyladenosine-3'-O-(2-cyanoethyl N, N-diisopropylphosphoramidite) 
• 210096-44-9 2'-O-(1-propyn-3-yl)-6-N-benzoyladenosine 
• 1208867-32-6 2'-O-((3-phenylisoxazol-5-yl)methyl)adenosine 
• 1285573-86-5 4-(3-(2'-O-adenosinyl)prop-1-yn-1-yl)benzaldehyde 
• 1285573-20-7 2'-O-((3-cyclohexylisoxazol-5-yl)methyl)adenosine 
• 1285573-70-7 4-(3-(2'-O-adenosinyl)prop-1-yn-1-yl)benzaldoxime 

Relevant articles and documents

CLASS A GPCR-BINDING COMPOUND MODIFIER

To provide a novel class-A GPCR antagonist, a production method therefor, or a novel compound that interacts with a Na+-water cluster binding site of a class-A GPCR. Used is a compound or a salt thereof comprising a structure comprising a class