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2'-O-Propargyladenosine is a modified nucleoside that features a propargyl group attached to the 2' position of the ribose ring of adenosine. This unique chemical modification significantly influences the properties and functions of adenosine within biological systems, making it a versatile compound for various applications in both biological and chemical research.

151390-97-5

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151390-97-5 Usage

Uses

Used in Enzyme Substrates:
2'-O-Propargyladenosine is used as a substrate for enzymes such as adenosine deaminase, playing a crucial role in the study and regulation of enzymatic activity related to adenosine metabolism.
Used in Pharmaceutical Development:
In the pharmaceutical industry, 2'-O-Propargyladenosine is used as a potential component in the development of new therapeutic agents. Its unique structure allows for targeted interactions with biological systems, offering opportunities for the creation of novel treatments.
Used in Bioconjugation and Click Chemistry:
2'-O-Propargyladenosine is utilized in bioconjugation and click chemistry reactions due to the reactivity of its propargyl group. It can participate in copper-catalyzed azide-alkyne cycloaddition reactions, enabling the formation of new chemical bonds and the creation of complex molecular structures for various applications in chemical synthesis and materials science.
Overall, 2'-O-Propargyladenosine's diverse applications highlight its potential as a valuable tool in both the life sciences and chemical research fields, with implications for the advancement of medicine, materials, and chemical technologies.

Check Digit Verification of cas no

The CAS Registry Mumber 151390-97-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,1,3,9 and 0 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 151390-97:
(8*1)+(7*5)+(6*1)+(5*3)+(4*9)+(3*0)+(2*9)+(1*7)=125
125 % 10 = 5
So 151390-97-5 is a valid CAS Registry Number.

151390-97-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2'-O-(propargyl)adenosine

1.2 Other means of identification

Product number -
Other names 2'-O-propargyl-adenosine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:151390-97-5 SDS

151390-97-5Relevant academic research and scientific papers

CLASS A GPCR-BINDING COMPOUND MODIFIER

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Paragraph 0203; 0223-0224, (2020/07/14)

To provide a novel class-A GPCR antagonist, a production method therefor, or a novel compound that interacts with a Na+-water cluster binding site of a class-A GPCR. Used is a compound or a salt thereof comprising a structure comprising a class

Synthesis and incorporation of a furan-modified adenosine building block for DNA interstrand crosslinking

Jawalekar, Anup M.,Op De Beeck, Marieke,Van Delft, Floris L.,Madder, Annemieke

supporting information; experimental part, p. 2796 - 2798 (2011/05/05)

2′-O-(3-(Furan-2-yl)propyl)adenosine was synthesized and evaluated for interstrand crosslink (ICL) formation in DNA duplexes. In situ oxidation of the furan moiety with NIS showed rapid crosslink formation to dA and dC, while dT and dG were inactive. The

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