151433-89-5

Upstream product

• 135851-09-1 3-(2,3,5-trichlorophenyl)pentanedinitrile 
• 5680-79-5 glycine ethyl ester hydrochloride 
• 135851-10-4 2-formyl-3-(2,3,5-trichlorophenyl)pentanedinitrile 
• 56961-75-2 2,3,5-trichlorobenzaldehyde 

Downstream Products

• 135851-16-0 N-benzoyl-N'-<4-<2-cyano-1-(2,3,5-trichlorophenyl)ethyl>-2-(methoxycarbonyl)-1H-pyrrol-3-yl>-S-methylthiourea 
• 135851-15-9 N-benzoyl-N'-<4-<2-cyano-1-(2,3,5-trichlorophenyl)ethyl>-2-(methoxycarbonyl)-1H-pyrrol-3-yl>thiourea 
• 135851-18-2 3-(2-amino-4-oxo-3H,5H-pyrrolo<3,2-d>pyrimidin-7-yl)-3-(2,3,5-trichlorophenyl)propanenitrile 
• 135851-14-8 methyl 3-amino-4-<2-cyano-1-(2,3,5-trichlorophenyl)ethyl>-1H-pyrrole-2-carboxylate 
• 151332-13-7 methyl 3-(2-amino-4-oxo-3H,5H-pyrrolo<3,2-d>pyrimidin-7-yl)-3-(3-chlorophenyl)propanoate 
• 151332-14-8 3-(2-amino-4-oxo-3H,5H-pyrrolo<3,2-d>pyrimidin-7-yl)-3-(3-chlorophenyl)propanol 
• 135851-21-7 3-(2-amino-4-oxo-3H,5H-pyrrolo<3,2-d>pyrimidin-7-yl)-3-phenylpropanoic acid 
• 135850-99-6 3-(2-amino-4-oxo-3H,5H-pyrrolo<3,2-d>pyrimidin-7-yl)-3-phenylpropanenitrile 
• 135851-13-7 1-ethyl 2-methyl 3-amino-4-<2-cyano-1-(2,3,5-trichlorophenyl)ethyl>-1H-pyrrole-1,2-dicarboxylate 

Relevant academic research and scientific papers

Structure-Based Design of Inhibitors of Purine Nucleoside Phosphorylase. 3. 9-Arylmethyl Derivatives of 9-Deazaguanine Substituted on the Methylene Group

X-ray crystallography and computer-assisted molecular modeling (CAMM) studies aided in the design of a potent series of Mammalian purine nucleoside phosphorylase (PNP) inhibitors.Enhanced potency was achieved by designing substituted 9-(arylmethyl)-9-deaz