151467-35-5Relevant academic research and scientific papers
First Reported Nonpeptide AT1 Receptor Agonist (L-162,313) Acts as an AT2 Receptor Agonist in Vivo
Wan, Yiqian,Wallinder, Charlotta,Johansson, Berndt,Holm, Mathias,Mahalingam,Wu, Xiongyu,Botros, Milad,Karlén, Anders,Pettersson, Anders,Nyberg, Fred,F?ndriks, Lars,Hallberg, Anders,Alterman, Mathias
, p. 1536 - 1546 (2004)
In this investigation, it is demonstrated that the first nonpeptide AT 1 receptor agonist L-162,313 (1), disclosed in 1994, also acts as an agonist at the AT2 receptor. In anesthetized rats, administration of compound 1 intravenously
Pharmaceutical treatment methods using angiotensin II receptor agonists bearing a thiophene moiety
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, (2008/06/13)
This invention relates to compounds represented by formula I: STR1 which are agonists of angiotensin II. The invention is also concerned with the use of aforementioned agonists in the treatment of states meditated by angiotensin.
