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15148-80-8

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15148-80-8 Usage

General Description

3-(tert-butylamino)-1-[(6-chloro-m-tolyl)oxy]propan-2-ol hydrochloride is a chemical compound with the molecular formula C15H24ClNO2. It is a hydrochloride salt of 3-(tert-butylamino)-1-[(6-chloro-m-tolyl)oxy]propan-2-ol, which is a beta-adrenergic receptor agonist. 3-(tert-butylamino)-1-[(6-chloro-m-tolyl)oxy]propan-2-ol hydrochloride is commonly used as a bronchodilator to treat asthma and other respiratory conditions. It works by relaxing the smooth muscles in the airways, allowing easier breathing. The hydrochloride salt form of the compound is more water-soluble, which allows for easier administration and absorption in the body.

Check Digit Verification of cas no

The CAS Registry Mumber 15148-80-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,1,4 and 8 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 15148-80:
(7*1)+(6*5)+(5*1)+(4*4)+(3*8)+(2*8)+(1*0)=98
98 % 10 = 8
So 15148-80-8 is a valid CAS Registry Number.
InChI:InChI=1/C14H22ClNO2.ClH/c1-10-5-6-12(15)13(7-10)18-9-11(17)8-16-14(2,3)4;/h5-7,11,16-17H,8-9H2,1-4H3;1H

15148-80-8Relevant articles and documents

Synthesis, phase behavior and absolute configuration of β-adrenoblocker bupranolol and related compounds

Bredikhin, Alexander A.,Bredikhina, Zemfira A.,Kurenkov, Alexey V.,Zakharychev, Dmitry V.,Gubaidullin, Aidar T.

, p. 157 - 165 (2018/07/25)

β-Blocker bupranolol 1, it's hydrochloride and their precursors 1-(2-chloro-5-methylphenoxy)-2,3-epoxypropane 2 and 3-(2-chloro-5-methylphenoxy)propane-1,2-diol 3 were prepared in racemic and single-enantiomer forms. For all the studied compounds phase behavior during crystallization was established on the basis of IR, DSC and X-ray investigations. Absolute configurations were established for compounds 1 and 2. Being conglomerate, racemic oxirane 2 was resolved by direct entrainment procedure. Being anticonglomerate, in the process of recrystallization, almost enantiopure 1·HCl accumulates in the mother liquor, not in the crystalline precipitate.

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