15148-80-8 Usage
Uses
Used in Pharmaceutical Industry:
3-(tert-butylamino)-1-[(6-chloro-m-tolyl)oxy]propan-2-ol hydrochloride is used as a bronchodilator for the treatment of respiratory conditions such as asthma. It functions by relaxing the smooth muscles in the airways, facilitating easier breathing for patients suffering from these conditions.
The hydrochloride salt form of the compound enhances its water solubility, which is beneficial for easier administration and absorption in the body. This improved solubility allows for more effective delivery of the compound to the target sites within the respiratory system, ensuring optimal therapeutic effects.
Check Digit Verification of cas no
The CAS Registry Mumber 15148-80-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,1,4 and 8 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 15148-80:
(7*1)+(6*5)+(5*1)+(4*4)+(3*8)+(2*8)+(1*0)=98
98 % 10 = 8
So 15148-80-8 is a valid CAS Registry Number.
InChI:InChI=1/C14H22ClNO2.ClH/c1-10-5-6-12(15)13(7-10)18-9-11(17)8-16-14(2,3)4;/h5-7,11,16-17H,8-9H2,1-4H3;1H
15148-80-8Relevant academic research and scientific papers
Synthesis, phase behavior and absolute configuration of β-adrenoblocker bupranolol and related compounds
Bredikhin, Alexander A.,Bredikhina, Zemfira A.,Kurenkov, Alexey V.,Zakharychev, Dmitry V.,Gubaidullin, Aidar T.
, p. 157 - 165 (2018/07/25)
β-Blocker bupranolol 1, it's hydrochloride and their precursors 1-(2-chloro-5-methylphenoxy)-2,3-epoxypropane 2 and 3-(2-chloro-5-methylphenoxy)propane-1,2-diol 3 were prepared in racemic and single-enantiomer forms. For all the studied compounds phase behavior during crystallization was established on the basis of IR, DSC and X-ray investigations. Absolute configurations were established for compounds 1 and 2. Being conglomerate, racemic oxirane 2 was resolved by direct entrainment procedure. Being anticonglomerate, in the process of recrystallization, almost enantiopure 1·HCl accumulates in the mother liquor, not in the crystalline precipitate.
